Related references
Note: Only part of the references are listed.Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses
Oleg Timofeev et al.
EMBO JOURNAL (2019)
Discussion of some knowns' and some unknowns' about the tumour suppressor p53
Elizabeth Lieschke et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2019)
p53 is required for female germline stem cell maintenance in P-element hybrid dysgenesis
Sadia Tasnim et al.
DEVELOPMENTAL BIOLOGY (2018)
Mitochondrial DNA replication in mammalian cells: overview of the pathway
Maria Falkenberg
MITOCHONDRIAL DISEASES (2018)
Centrosome amplification arises before neoplasia and increases upon p53 loss in tumorigenesis
Carla A. M. Lopes et al.
JOURNAL OF CELL BIOLOGY (2018)
DNA repair processes are critical mediators of p53-dependent tumor suppression
Ana Janic et al.
NATURE MEDICINE (2018)
p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POL theta pathways
Sunetra Roy et al.
ELIFE (2018)
The Tip of an Iceberg: Replication-Associated Functions of the Tumor Suppressor p53
Vanesa Gottifredi et al.
CANCERS (2018)
Mechanisms of transcriptional regulation by p53
Kelly D. Sullivan et al.
CELL DEATH AND DIFFERENTIATION (2018)
Serine 392 phosphorylation modulates p53 mitochondrial translocation and transcription-independent apoptosis
Cedric Castrogiovanni et al.
CELL DEATH AND DIFFERENTIATION (2018)
How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?
Brandon J. Aubrey et al.
CELL DEATH AND DIFFERENTIATION (2018)
Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin
Kang Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
p53 genes function to restrain mobile elements
Annika Wylie et al.
GENES & DEVELOPMENT (2016)
P53 and the defenses against genome instability caused by transposons and repetitive elements
Arnold J. Levine et al.
BIOESSAYS (2016)
p53 in the game of transposons
Annika Wylie et al.
BIOESSAYS (2016)
An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model
Matthew Jennis et al.
GENES & DEVELOPMENT (2016)
DNA damage tolerance pathway involving DNA polymerase ι and the tumor suppressor p53 regulates DNA replication fork progression
Stephanie Hamppa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
p53 Maintains Genomic Stability by Preventing Interference between Transcription and Replication
Constance Qiao Xin Yeo et al.
CELL REPORTS (2016)
p53 in the DNA-Damage-Repair Process
Ashley B. Williams et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)
A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining
Sylvie Moureau et al.
OPEN BIOLOGY (2016)
53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis
Chii Shyang Fong et al.
eLife (2016)
Pin1-Induced Proline Isomerization in Cytosolic p53 Mediates BAX Activation and Apoptosis
Ariele Viacava Follis et al.
MOLECULAR CELL (2015)
Loss of p53 and altered miR15-a/16-1 → MCL-1 pathway in CLL: insights from TCL1-Tg:p53-/- mouse model and primary human leukemia cells
J. Liu et al.
LEUKEMIA (2014)
Centrosomes back in the limelight Introduction
Michel Bornens et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death
S. Oka et al.
ONCOGENESIS (2014)
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
G. Sorrentino et al.
CELL DEATH AND DIFFERENTIATION (2013)
Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling
Julia M. Sidorova et al.
DNA REPAIR (2013)
eRNAs Are Required for p53-Dependent Enhancer Activity and Gene Transcription
Carlos A. Melo et al.
MOLECULAR CELL (2013)
p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation
T. Rieckmann et al.
ONCOGENE (2013)
p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa
Liz J. Valente et al.
CELL REPORTS (2013)
p53-dependent regulation of Mcl-1 contributes to synergistic cell death by ionizing radiation and the Bcl-2/Bcl-XL inhibitor ABT-737
Katrin E. Tagscherer et al.
APOPTOSIS (2012)
Tumor Suppression in the Absence of p53-Mediated Cell-Cycle Arrest, Apoptosis, and Senescence
Tongyuan Li et al.
CELL (2012)
p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis
Angelina V. Vaseva et al.
CELL (2012)
Centrosome Aberrations Associated with Cellular Senescence and p53 Localization at Supernumerary Centrosomes
Susumu Ohshima
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Distinct p53 Transcriptional Programs Dictate Acute DNA-Damage Responses and Tumor Suppression
Colleen A. Brady et al.
CELL (2011)
ATR-p53 Restricts Homologous Recombination in Response to Replicative Stress but Does Not Limit DNA Interstrand Crosslink Repair in Lung Cancer Cells
Bianca M. Sirbu et al.
PLOS ONE (2011)
Maximal killing of lymphoma cells by DNA damage-inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim
Lina Happo et al.
BLOOD (2010)
Inhibition of centriole duplication by centrobin depletion leads to p38-p53 mediated cell-cycle arrest
Libing Song et al.
CELLULAR SIGNALLING (2010)
Regulation of the p53 transcriptional response by structurally diverse core promoters
Jose M. Morachis et al.
GENES & DEVELOPMENT (2010)
Mutant p53 Drives Invasion by Promoting Integrin Recycling
Patricia A. J. Muller et al.
CELL (2009)
Dissection of the sequence-specific DNA binding and exonuclease activities reveals a superactive yet apoptotically impaired mutant p53 protein
Jinwoo Ahn et al.
CELL CYCLE (2009)
Modifications of p53: competing for the lysines
Stephanie Carter et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2009)
p53 responsive elements in human retrotransposons
C. R. Harris et al.
ONCOGENE (2009)
Timed Somatic Deletion of p53 in Mice Reveals Age-Associated Differences in Tumor Progression
George Hinkal et al.
PLOS ONE (2009)
Posttranslational Modification of p53: Cooperative Integrators of Function
David W. Meek et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
Multiple p53-independent gene silencing mechanisms define the cellular response to p53 activation
Ramiro Paris et al.
CELL CYCLE (2008)
DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells
Zhiyong Mao et al.
CELL CYCLE (2008)
In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute
E. M. Michalak et al.
CELL DEATH AND DIFFERENTIATION (2008)
Regulation of clathrin-mediated endocytosis by p53
Yoshie Endo et al.
GENES TO CELLS (2008)
Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain
E. Christine Pietsch et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Dissecting the role of p53 phosphorylation in homologous recombination provides new clues for gain-of-function mutants
Anja Restle et al.
NUCLEIC ACIDS RESEARCH (2008)
Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53
Ting Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Modulation of p53 function by SET8-mediated methylation at lysine 382
Xiaobing Shi et al.
MOLECULAR CELL (2007)
p53-mediated activation of miRNA34 candidate tumor-suppressor genes
Guido T. Bommer et al.
CURRENT BIOLOGY (2007)
Direct evidence for the role of centrosomally localized p53 in the regulation of centrosome duplication
K. Shinmura et al.
ONCOGENE (2007)
P53 gain-of-function cancer mutants induce genetic instability by inactivating ATM
Hoseok Song et al.
NATURE CELL BIOLOGY (2007)
Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53-dependent cellular senescence
Wilfredo Cosme-Blanco et al.
EMBO REPORTS (2007)
Loss of centrosome integrity induces p38-p53-p21dependent G1-S arrest
Keith Mikule et al.
NATURE CELL BIOLOGY (2007)
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation
Aaheli Roy Choudhury et al.
NATURE GENETICS (2007)
The pathological response to DNA damage does not contribute to p53-mediated tumour suppression
M. A. Christophorou et al.
NATURE (2006)
Policing of oncogene activity by p53
Alejo Efeyan et al.
NATURE (2006)
Transcriptional regulation by p53: one protein, many possibilities
O. Laptenko et al.
CELL DEATH AND DIFFERENTIATION (2006)
p53 in recombination and repair
S. A. Gatz et al.
CELL DEATH AND DIFFERENTIATION (2006)
The effect of p53-RNAi and p53 knockout on human 8-oxoguanine DNA glycosylase (hOgg1) activity
A Chatterjee et al.
FASEB JOURNAL (2005)
G1 checkpoint failure and increased tumor susceptibility in mice lacking the novel p53 target Ptprv
G Doumont et al.
EMBO JOURNAL (2005)
Transcription-independent suppression of DNA synthesis by p53 in sperm-irradiated mouse zygotes
M Toyoshima et al.
ONCOGENE (2005)
Transcriptional control of BubR1 by p53 and suppression of centrosome amplification by BubR1
T Oikawa et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Modulation of p53 binding to Holliday junctions and 3-cytosine bulges by phosphorylation events
D Subramanian et al.
BIOCHEMISTRY (2005)
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex
JIJ Leu et al.
NATURE CELL BIOLOGY (2004)
p53 protects from replication-associated DNA double-strand breaks in mammalian cells
A Kumari et al.
ONCOGENE (2004)
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
JE Chipuk et al.
SCIENCE (2004)
Recombination at chromosomal sequences involved in leukaemogenic rearrangements is differentially regulated by p53
GS Boehden et al.
CARCINOGENESIS (2004)
p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation
A Tritarelli et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
The interaction of p53 with replication protein A mediates suppression of homologous recombination
LY Romanova et al.
ONCOGENE (2004)
Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
G Liu et al.
NATURE GENETICS (2004)
P53′s double life:: transactivation-independent repression of homologous recombination
P Bertrand et al.
TRENDS IN GENETICS (2004)
Replication of damaged DNA in vitro is blocked by p53
JM Zhou et al.
NUCLEIC ACIDS RESEARCH (2003)
p53 mutated in the transactivation domain retains regulatory functions in homology-directed double-strand break repair
GS Boehden et al.
ONCOGENE (2003)
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
S Sengupta et al.
EMBO JOURNAL (2003)
p53 has a direct apoptogenic role at the mitochondria
M Mihara et al.
MOLECULAR CELL (2003)
p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage
CP Rubbi et al.
EMBO JOURNAL (2003)
p53-associated 3′→5′ exonuclease activity in nuclear and cytoplasmic compartments of cells
L Gila et al.
ONCOGENE (2003)
Loss of p53 and centrosome hyperamplification
P Tarapore et al.
ONCOGENE (2002)
DNA substrate dependence of p53-mediated regulation of double-strand break repair
N Akyüz et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The processing of Holliday junctions by BLM and WRN helicases is regulated by p53
Q Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Wild-type p53 inhibits replication-associated homologous recombination
C Janz et al.
ONCOGENE (2002)
Association of p53 and MSH2 with recombinative repair complexes during S phase
D Zink et al.
ONCOGENE (2002)
Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor
DJ Derbyshire et al.
EMBO JOURNAL (2002)
Interactions between p53, hMSH2-hMSH6 and HMG I(Y) on Holliday junctions and bulged bases
D Subramanian et al.
NUCLEIC ACIDS RESEARCH (2002)
p53 binds and activates the xeroderma pigmentosum DDB2 gene in humans but not mice
T Tan et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
A conserved intronic response element mediates direct p53-dependent transcriptional activation of both the human and murine bax genes
EC Thornborrow et al.
ONCOGENE (2002)
Difference in the centrosome duplication regulatory activity among p53 'hot spot' mutants: potential role of Ser 315 phosphorylation-dependent centrosome binding of p53
P Tarapore et al.
ONCOGENE (2001)
APAF1 is a key transcriptional target for p53 in the regulation of neuronal cell death
A Fortin et al.
JOURNAL OF CELL BIOLOGY (2001)
p53 modulates the exonuclease activity of Werner syndrome protein
RM Brosh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Apaf-1 is a transcriptional target for E2F and p53
MC Moroni et al.
NATURE CELL BIOLOGY (2001)
p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle
M Ciciarello et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Direct regulation of the centrosome duplication cycle by the p53-p21Waf1/Cip1 pathway
P Tarapore et al.
ONCOGENE (2001)
PUMA induces the rapid apoptosis of colorectal cancer cells
J Yu et al.
MOLECULAR CELL (2001)
PUMA, a novel proapoptotic gene, is induced by p53
K Nakano et al.
MOLECULAR CELL (2001)
A role for p53 in base excision repair
JM Zhou et al.
EMBO JOURNAL (2001)
Structural and functional involvement of p53 in BER in vitro and in vivo
H Offer et al.
ONCOGENE (2001)
p53 and c-Jun functionally synergize in the regulation of the DNA repair gene hMSH2 in response to UV
SJ Scherer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Death signal-induced localization of p53 protein to mitochondria - A potential role in apoptotic signaling
ND Marchenko et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer
AT Ferguson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Nora, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis
E Oda et al.
SCIENCE (2000)
Share Paper
