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NEUROLOGY (2011)
Towards a whole-body systems [multi-organ] lipidomics in Alzheimer's disease
Giuseppe Astarita et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2011)
Metabolome in progression to Alzheimer's disease
M. Oresic et al.
TRANSLATIONAL PSYCHIATRY (2011)
Higher Incidence of Mild Cognitive Impairment in Familial Hypercholesterolemia
Daniel Zambon et al.
AMERICAN JOURNAL OF MEDICINE (2010)
Isoprenoids, small GTPases and Alzheimer's disease
Gero P. Hooff et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
Phospholipase D in brain function and Alzheimer's disease
Tiago Gil Oliveira et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2010)
ABC efflux transporters in brain vasculature of Alzheimer's subjects
Hasini C. Wijesuriya et al.
BRAIN RESEARCH (2010)
Lipid rafts: Keys to neurodegeneration
Cara-Lynne Schengrund
BRAIN RESEARCH BULLETIN (2010)
The ATP-Binding Cassette Transporter-2 (ABCA2) Increases Endogenous Amyloid Precursor Protein Expression and Abeta Fragment Generation
W. Davis
CURRENT ALZHEIMER RESEARCH (2010)
Lipid Alterations in Lipid Rafts from Alzheimer's Disease Human Brain Cortex
Virginia Martin et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Leptin Reduces the Accumulation of A beta and Phosphorylated Tau Induced by 27-Hydroxycholesterol in Rabbit Organotypic Slices
Gurdeep Marwarha et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
ABCG2 reduces ROS-mediated toxicity and inflammation: a potential role in Alzheimer's disease
Shanshan Shen et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Circulating plasmalogen levels and Alzheimer Disease Assessment Scale-Cognitive scores in Alzheimer patients
Paul L. Wood et al.
JOURNAL OF PSYCHIATRY & NEUROSCIENCE (2010)
The Pathogenic Implication of Abnormal Interaction Between Apolipoprotein E Isoforms, Amyloid-beta Peptides, and Sulfatides in Alzheimer's Disease
Xianlin Han
MOLECULAR NEUROBIOLOGY (2010)
Apolipoprotein E mediates sulfatide depletion in animal models of Alzheimer's disease
Hua Cheng et al.
NEUROBIOLOGY OF AGING (2010)
Deregulation of sphingolipid metabolism in Alzheimer's disease
Xingxuan He et al.
NEUROBIOLOGY OF AGING (2010)
Fatty Acid Composition of Frontal, Temporal and Parietal Neocortex in the Normal Human Brain and in Alzheimer's Disease
Thomas Fraser et al.
NEUROCHEMICAL RESEARCH (2010)
Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease LEADe
H. H. Feldman et al.
NEUROLOGY (2010)
Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease
Giuseppe Astarita et al.
PLOS ONE (2010)
Omega-3 fatty acids and risk of dementia: the Canadian Study of Health and Aging
Edeltraut Kroeger et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)
Cerebrospinal Fluid Secretory Ca2+-Dependent Phospholipase A2 Activity Is Increased in Alzheimer Disease
Sonia Chalbot et al.
CLINICAL CHEMISTRY (2009)
Health effects of trans-fatty acids: experimental and observational evidence
D. Mozaffarian et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2009)
Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography
John C. Umhau et al.
JOURNAL OF LIPID RESEARCH (2009)
ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood-Brain Barrier for Aβ1-40 Peptides
Huaqi Xiong et al.
JOURNAL OF NEUROSCIENCE (2009)
DHA and cholesterol containing diets influence Alzheimer-like pathology, cognition and cerebral vasculature in APP(swe)/PS1(dE9) mice
C. R. Hooijmans et al.
NEUROBIOLOGY OF DISEASE (2009)
Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial
Samuel T. Henderson et al.
NUTRITION & METABOLISM (2009)
Can the rat liver maintain normal brain DHA metabolism in the absence of dietary DHA?
Stanley I. Rapoport et al.
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS (2009)
Brain Glucose Hypometabolism and Oxidative Stress in Preclinical Alzheimer's Disease
Lisa Mosconi et al.
MITOCHONDRIA AND OXIDATIVE STRESS IN NEURODEGENERATIVE DISORDERS (2008)
Multiple roles of phosphoinositide-specific phospholipase C isozymes
Pann-Ghill Suh et al.
BMB REPORTS (2008)
Reduced risk of incident AD with elective statin use in a clinical trial cohort
D. Larry Sparks et al.
CURRENT ALZHEIMER RESEARCH (2008)
Obesity and Hypertriglyceridemia produce cognitive impairment
Susan A. Farr et al.
ENDOCRINOLOGY (2008)
Cholesterol depletion inhibits synaptic transmission and synaptic plasticity in rat hippocampus
C. Frank et al.
EXPERIMENTAL NEUROLOGY (2008)
Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease
Suzanne E. Wahrle et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Formation of toxic Aβ(1-40) fibrils on GM1 ganglioside-containing membranes mimicking lipid rafts:: Polymorphisms in Aβ(1-40) fibrils
Takuma Okada et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
The ketogenic diet increases mitochondrial glutathione levels
Stuart G. Jarrett et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Retinoic Acid Attenuates β-Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model
Yun Ding et al.
JOURNAL OF NEUROSCIENCE (2008)
Effect of Dietary n-3 Polyunsaturated Fatty Acids on Brain Lipid Fatty Acid Composition, Learning Ability, and Memory of Senescence-Accelerated Mouse
Anna L. Petursdottir et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2008)
Mitochondrial dysfunction in rat brain with aging Involvement of complex I, reactive oxygen species and cardiolipin
G. Petrosillo et al.
NEUROCHEMISTRY INTERNATIONAL (2008)
The opposing effects of n-3 and n-6 fatty acids
Gerd Schmitz et al.
PROGRESS IN LIPID RESEARCH (2008)
Ceramide triggers budding of exosome vesicles into multivesicular Endosomes
Katarina Trajkovic et al.
SCIENCE (2008)
Longitudinal CSF isoprostane and MRI atrophy in the progression to AD
M. J. de Leon et al.
JOURNAL OF NEUROLOGY (2007)
A neuroscientist's guide to lipidomics
Daniele Piomelli et al.
NATURE REVIEWS NEUROSCIENCE (2007)
Active β-amyloid immunization restores spatial learning in PDAPP mice displaying very low levels of β-amyloid
Guiquan Chen et al.
JOURNAL OF NEUROSCIENCE (2007)
Plasma phosphatidylcholine docosahexaenoic acid content and risk of dementia and Alzheimer disease - The Framingham heart study
Ernst J. Schaefer et al.
ARCHIVES OF NEUROLOGY (2006)
Phosphoinositides in cell regulation and membrane dynamics
Gilbert Di Paolo et al.
NATURE (2006)
ω-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease:: OmegAD study -: A randomized double-blind trial
Yvonne Freund-Levi et al.
ARCHIVES OF NEUROLOGY (2006)
Impact of different saturated fatty acid, polyunsaturated fatty acid and cholesterol containing diets on beta-amyloid accumulation in APP/PS1 transgenic mice
M. Oksman et al.
NEUROBIOLOGY OF DISEASE (2006)
ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages
Andreas W. Jehle et al.
JOURNAL OF CELL BIOLOGY (2006)
Mitochondrial biogenesis in the anticonvulsant mechanism of the ketogenic diet
Kristopher J. Bough et al.
ANNALS OF NEUROLOGY (2006)
Binding of amyloid β-peptide to ganglioside micelles is dependent on histidine-13
Mike P. Williamson et al.
BIOCHEMICAL JOURNAL (2006)
High cholesterol content in neurons increases BACE, β-amyloid, and phosphorylated tau levels in rabbit hippocampus
Othman Ghribi et al.
EXPERIMENTAL NEUROLOGY (2006)
Identity of SMCT1 (SLC5A8) as a neuron-specific Na+-coupled transporter for active uptake of L-lactate and ketone bodies in the brain
Pamela M. Martin et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells
Woojin S. Kim et al.
NEUROREPORT (2006)
Prolyl endopeptidase inhibitory activity of unsaturated fatty acids
YS Park et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)
Deletion of Abca1 increases Aβ deposition in the PDAPP transgenic mouse model of Alzheimer disease
SE Wahrle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Deletion of the prostaglandin E2 EP2 receptor reduces oxidative damage and amyloid burden in a model of Alzheimer's disease
XB Liang et al.
JOURNAL OF NEUROSCIENCE (2005)
Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment
WR Markesbery et al.
ANNALS OF NEUROLOGY (2005)
Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin
MOW Grimm et al.
NATURE CELL BIOLOGY (2005)
GM1 ganglioside prevented the decline of hippocampal neurogenesis associated with D-galactose
Q Zhang et al.
NEUROREPORT (2005)
Inhibition of glycosphingolipid biosynthesis reduces secretion of the β-amyloid precursor protein and amyloid β-peptide
IY Tamboli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Cholesterol homeostasis in neurons and glial cells
JE Vance et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2005)
Astroglial expression of ceramide in Alzheimer's disease brains: A role during neuronal apoptosis
H Satoi et al.
NEUROSCIENCE (2005)
Dimeric amyloid β protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease
T Kawarabayashi et al.
JOURNAL OF NEUROSCIENCE (2004)
The ketogenic diet increases mitochondrial uncoupling protein levels and activity
PG Sullivan et al.
ANNALS OF NEUROLOGY (2004)
Connection of lipid peroxide oxidation with the sphingomyelin pathway in the development of Alzheimer's disease
AV Alessenko et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2004)
ApoE and clusterin cooperatively suppress Aβ levels and deposition:: Evidence that ApoE regulates extracellular Aβ metabolism in vivo
RB DeMattos et al.
NEURON (2004)
Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway
JT Lee et al.
JOURNAL OF CELL BIOLOGY (2004)
ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE
SE Wahrle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
A nontransgenic mouse model shows inducible amyloid-β (Aβ) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade
I Dolev et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Disruption of the retinoid signalling pathway causes a deposition of amyloid β in the adult rat brain
JPT Corcoran et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Neuronal membrane cholesterol loss enhances amyloid pepticle generation
J Abad-Rodriguez et al.
JOURNAL OF CELL BIOLOGY (2004)
Fatty acids increase presenilin-1 levels and γ-secretase activity in PSwt-1 cells
YZ Liu et al.
JOURNAL OF LIPID RESEARCH (2004)
Involvement of arachidonic acid cascade in working memory impairment induced by interleukin-1 beta
Y Matsumoto et al.
NEUROPHARMACOLOGY (2004)
APOE genotype effects on Alzheimer's disease onset and epidemiology
JW Ashford
JOURNAL OF MOLECULAR NEUROSCIENCE (2004)
Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia
XL Han et al.
ANNALS OF NEUROLOGY (2003)
Alzheimer's disease: the cholesterol connection
L Puglielli et al.
NATURE NEUROSCIENCE (2003)
Dietary fats and the risk of incident Alzheimer disease
MC Morris et al.
ARCHIVES OF NEUROLOGY (2003)
Ketogenic diet increases glutathione peroxidase activity in rat hippocampus
DR Ziegler et al.
NEUROCHEMICAL RESEARCH (2003)
Plasma antioxidants are similarly depleted in mild cognitive impairment and in Alzheimer's disease
P Rinaldi et al.
NEUROBIOLOGY OF AGING (2003)
Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial
J Shepherd et al.
LANCET (2002)
Gluing the respiratory chain together - Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane
M Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Sphingomyelinases:: enzymology and membrane activity
FM Goñi et al.
FEBS LETTERS (2002)
Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease:: A 26-week randomized, placebo-controlled, double-blind trial
M Simons et al.
ANNALS OF NEUROLOGY (2002)
Peripheral F2-isoprostanes and F4-neuroprostanes are not increased in Alzheimer's disease
TJ Montine et al.
ANNALS OF NEUROLOGY (2002)
Substantial sulfatide deficiency and ceramide elevation in very early Alzheimer's disease: potential role in disease pathogenesis
XL Han et al.
JOURNAL OF NEUROCHEMISTRY (2002)
MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20536 high-risk individuals: a randomised placebo-controlled trial
R Collins et al.
LANCET (2002)
Breath acetone is a reliable indicator of ketosis in adults consuming ketogenic meals
K Musa-Veloso et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2002)
Aluminum modulates brain amyloidosis through oxidative stress in APP transgenic mice
D Praticó et al.
FASEB JOURNAL (2002)
Human and murine ApoE markedly alters Aβ metabolism before and after plaque formation in a mouse model of Alzheimer's disease
AM Fagan et al.
NEUROBIOLOGY OF DISEASE (2002)
Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people
K Rockwood et al.
ARCHIVES OF NEUROLOGY (2002)
Alzheimer disease - Effect of continuous intracerebroventricular treatment with GM1 ganglioside and a systematic activation programme
L Svennerholm et al.
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS (2002)
24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia
A Papassotiropoulos et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2002)
Enhancement of phospholipase D activity by overexpression of amyloid precursor protein in P19 mouse embryonic carcinoma cells
MJ Lee et al.
NEUROSCIENCE LETTERS (2001)
CNS synaptogenesis promoted by glia-derived cholesterol
DH Mauch et al.
SCIENCE (2001)
Role of apoE/Aβ interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy
DM Holtzman
JOURNAL OF MOLECULAR NEUROSCIENCE (2001)
Brain membrane phospholipid alterations in Alzheimer's disease
JW Pettegrew et al.
NEUROCHEMICAL RESEARCH (2001)
Midlife vascular risk factors and Alzheimer's disease in later life:: longitudinal, population based study
M Kivipelto et al.
BMJ-BRITISH MEDICAL JOURNAL (2001)
Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the α-secretase ADAM 10
E Kojro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Plasmalogen deficiency in early Alzheimer's disease subjects and in animal models: molecular characterization using electrospray ionization mass spectrometry
XL Han et al.
JOURNAL OF NEUROCHEMISTRY (2001)
β-Amyloid efflux mediated by p-glycoprotein
FC Lam et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3) -: Role of phosphatidylserine in antiapoptotic effect
HY Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
LM Refolo et al.
NEUROBIOLOGY OF DISEASE (2000)
Plasma 24S-hydroxycholesterol:: a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer's disease
A Papassotiropoulos et al.
NEUROREPORT (2000)
D-β-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease
Y Kashiwaya et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
DM Holtzman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Modulation of β-amyloid precursor protein processing by the low density lipoprotein receptor-related protein (LRP) -: Evidence that LRP contributes to the pathogenesis of Alzheimer's disease
PG Ulery et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Effect of dietary docosahexaenoic acid and phosphatidylcholine on maze behavior and fatty acid composition of plasma and brain lipids in mice
SY Lim et al.
INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH (2000)