4.3 Letter

Wolcott-Rallison Syndrome-Endocrinopathy with Recurrent Acute Liver Failure

Journal

INDIAN PEDIATRICS
Volume 56, Issue 12, Pages 1055-1056

Publisher

SPRINGER INDIA
DOI: 10.1007/s13312-019-1688-y

Keywords

Diabetes mellitus; Genetic disorder; Metabolic disease; Recurrent acute liver failure; Skeletal dysplasia

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A 2-yr-old child with early onset diabetes and hypothyroidism, and diagnosed as Wolcott-Rallison Syndrome, developed two episodes of acute liver failure and recovered, but he remains at high risk of developing another episode of acute liver failure. Autoimmune, metabolic or genetic disorders should be evaluated in children with recurrent acute liver failure and genetic tests needs to be considered.

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