4.7 Review

Targeting cell death signalling in cancer: minimising 'Collateral damage'

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Resistance to HSP90 inhibition involving loss of MCL1 addiction

S. Busacca et al.

ONCOGENE (2016)

Article Medicine, General & Internal

Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia

Andrew W. Roberts et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Oncology

Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy

Bingshe Han et al.

CANCER CELL (2015)

Article Biochemistry & Molecular Biology

Drug-Induced Death Signaling Strategy Rapidly Predicts Cancer Response to Chemotherapy

Joan Montero et al.

Article Pharmacology & Pharmacy

Bcl-2 family of proteins as drug targets for cancer chemotherapy: the long way of BH3 mimetics from bench to bedside

Laura Vela et al.

CURRENT OPINION IN PHARMACOLOGY (2015)

Review Pharmacology & Pharmacy

Targeting TRAIL in the treatment of cancer: new developments

Bora Lim et al.

EXPERT OPINION ON THERAPEUTIC TARGETS (2015)

Article Oncology

A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma

Ravi K. Amaravadi et al.

MOLECULAR CANCER THERAPEUTICS (2015)

Review Pharmacology & Pharmacy

Small molecule Mcl-1 inhibitors for the treatment of cancer

Johannes Belmar et al.

PHARMACOLOGY & THERAPEUTICS (2015)

Article Multidisciplinary Sciences

A set of NF-κB-regulated microRNAs induces acquired TRAIL resistance in Lung cancer

Young-Jun Jeon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death

Octavian Bucur et al.

SCIENTIFIC REPORTS (2015)

Article Biochemistry & Molecular Biology

Smac mimetic promotes glioblastoma cancer stem-like cell differentiation by activating NF-KB

A. Tchoghandjian et al.

CELL DEATH AND DIFFERENTIATION (2014)

Article Cell Biology

Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure

Robert L. Thomas et al.

GENES & DEVELOPMENT (2013)

Article Cell Biology

Glucose-a sweet way to die Metabolic switching modulates tumor cell death

Marion MacFarlane et al.

CELL CYCLE (2012)

Review Oncology

The 'complexities' of life and death: Death receptor signalling platforms

Laura S. Dickens et al.

EXPERIMENTAL CELL RESEARCH (2012)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Article Multidisciplinary Sciences

Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy

Triona Ni Chonghaile et al.

SCIENCE (2011)

Article Biochemistry & Molecular Biology

Tyrosine dephosphorylation is required for Bak activation in apoptosis

Joanna L. Fox et al.

EMBO JOURNAL (2010)

Article Biochemistry & Molecular Biology

TRAIL treatment provokes mutations in surviving cells

M. M. Lovric et al.

ONCOGENE (2010)

Article Biochemistry & Molecular Biology

IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis

Eugene Varfolomeev et al.

Article Biochemistry & Molecular Biology

IAP antagonists target cIAP1 to induce TNFα- dependent apoptosis

James E. Vince et al.

Letter Oncology

Barriers to effective TRAIL-targeted therapy of malignancy

Martin J. S. Dyer et al.

JOURNAL OF CLINICAL ONCOLOGY (2007)