4.4 Article

CogEvo, a cognitive function balancer, is a sensitive and easy psychiatric test battery for age-related cognitive decline

Journal

GERIATRICS & GERONTOLOGY INTERNATIONAL
Volume 20, Issue 3, Pages 248-255

Publisher

WILEY
DOI: 10.1111/ggi.13847

Keywords

age-related cognitive decline; cognitive function balancer; computer-aided psychiatric test battery

Funding

  1. Ministry of Education, Science and Culture of Japan [18K07385, 19K07989]
  2. Grants-in-Aid for Scientific Research [19K07989, 18K07385] Funding Source: KAKEN

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Aim We examined whether a newly developed computer-aided neuropsychiatric series of test, CogEvo, is necessary and sufficient for the evaluation of cognitive function in older people. Methods A total of 272 participants in worthwhile life activity for the prevention of decline in mobility and cognitive function were administered tests every week at 33 locations in Fukaura-machi, Japan. Basic profile information, a Mini-Mental State Examination (MMSE), a CogEvo and a clock drawing test were used in the present study. Results Our results are summarized as: (i) the total score of the CogEvo and MMSE tests decreased significantly according to age and in age group analysis; (ii) scores from the CogEvo and MMSE tests showed a significant correlation; (iii) MMSE scores showed marked ceiling effects; (iv) analysis of cognitive domains, such as orientation, attention, memory and executive function, and spatial cognition using CogEvo showed significant age-dependent impairment; (v) CogEvo discriminated three score groups of MMSE results with sensitivity and specificity of 70% and 60% in the <23 score group, 78% and 54% in the 24-26 score group, and 85% and 70% in the >27 score group, respectively; (vi) CogEvo memory tests reflected more detailed recall function than registration function; and (vii) CogEvo spatial cognition test results were correlated with test items of the MMSE and clock drawing tests. Conclusions CogEvo is an easy and potentially useful computer-aided test battery that can be used to evaluate age-related or pathological decline in cognitive function from middle age and in preclinical stages of dementia. Geriatr Gerontol Int 2019; center dot center dot: center dot center dot-center dot center dot.

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