Journal
BREASTFEEDING MEDICINE
Volume 11, Issue 1, Pages 2-5Publisher
MARY ANN LIEBERT, INC
DOI: 10.1089/bfm.2015.0125
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Funding
- Canadian Institutes of Health Research (MOP) [125997]
- University of Toronto Post Graduate Medical Education Trainee Grant Program
- Elizabeth Arbuthnot Dyson Fellowship
- Joseph M. West Memorial Funds
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Background: Fecal calprotectin (fCP) is a biomarker of gastrointestinal tract (GIT) inflammation that is currently being used investigationally among very low birth weight (VLBW) infants. Materials and Methods: Stool was collected weekly from 20 breastmilk-fed VLBW infants for up to 8 weeks after birth during the establishment and fortification of feeds, and fCP concentrations were measured. Results: Mean fCP levels increased significantly in stools collected immediately following bovine-based nutrient fortification of feeds (p=0.005). Conclusions: Addition of bovine fortifier to breastmilk feeds appeared to be associated with an acute increase in GIT inflammation.
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