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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Targeting cell-impermeable prodrug activation to tumor microenvironment eradicates multiple drug-resistant neoplasms
WY Wu et al.
CANCER RESEARCH (2006)
Dipeptide-based highly potent doxorubicin antibody conjugates
SC Jeffrey et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Targeting proteases: successes, failures and future prospects
Boris Turk
NATURE REVIEWS DRUG DISCOVERY (2006)
Deregulated matriptase causes ras-independent multistage carcinogenesis and promotes ras-mediated malignant transformation
K List et al.
GENES & DEVELOPMENT (2005)
Cutaneous adverse effects with HER1/EGFR-targeted agents:: Is there a silver lining?
R Peréz-Soler et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
The matrix metalloproteinase-9/neutrophil gelatinase-associated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients
CA Fernández et al.
CLINICAL CANCER RESEARCH (2005)
Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery
XY Chen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis
JA Joyce et al.
CANCER CELL (2004)
Zymographic detection and clinical correlations of MMP-2 and MMP-9 in breast cancer sera
G La Rocca et al.
BRITISH JOURNAL OF CANCER (2004)
Review - Proteases, extracellular matrix, and cancer - A workshop of the path B study section
YA DeClerck et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies
JF DiJoseph et al.
BLOOD (2004)
Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation
J Chen et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)
Efficient elimination of B-lineage lymphomas by anti-CD20-auristatin conjugates
CL Law et al.
CLINICAL CANCER RESEARCH (2004)
Plasmodium falciparum cysteine protease falcipain-1 is not essential in erythrocytic stage malaria parasites
PS Sijwali et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Membrane associated proteases and their inhibitors in tumour angiogenesis
A Noel et al.
JOURNAL OF CLINICAL PATHOLOGY (2004)
Development of the proteasome inhihitor Veleade((TM)) (Bortezomib)
J Adams et al.
CANCER INVESTIGATION (2004)
cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity
JA Francisco et al.
BLOOD (2003)
Extracellular matrix remodelling: the role of matrix metalloproteinases
I Stamenkovic
JOURNAL OF PATHOLOGY (2003)
Human and mouse proteases:: A comparative genomic approach
XS Puente et al.
NATURE REVIEWS GENETICS (2003)
A phase 2 study of bortezomib in relapsed, refractory myeloma
PG Richardson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Human and parasitic papain-like cysteine proteases:: Their role in physiology and pathology and recent developments in inhibitor design
F Lecaille et al.
CHEMICAL REVIEWS (2002)
Serine protease mechanism and specificity
L Hedstrom
CHEMICAL REVIEWS (2002)
Structure and mechanism of the pepsin-like family of aspartic peptidases
BM Dunn
CHEMICAL REVIEWS (2002)
Thrombin functions during tissue factor-induced blood coagulation
KE Brummel et al.
BLOOD (2002)
Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: Model studies of enzymatic drug release and antigen-specific in vitro anticancer activity
GM Dubowchik et al.
BIOCONJUGATE CHEMISTRY (2002)
Substrate specificity of schistosome versus human legumain determined by P1-P3 peptide libraries
MA Mathieu et al.
MOLECULAR AND BIOCHEMICAL PARASITOLOGY (2002)
Star structure of antibody-targeted HPMA copolymer-bound doxorubicin: A novel type of polymeric conjugate for targeted drug delivery with potent antitumor effect
M Kovar et al.
BIOCONJUGATE CHEMISTRY (2002)
Cleavable linkers to enhance selectivity of antibody-targeted therapy of cancer
DL Kukis et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2001)
Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse
EL Sievers et al.
JOURNAL OF CLINICAL ONCOLOGY (2001)
Expression of invariant chain and pro-cathepsin L in Alzheimer's brain
Y Yoshiyama et al.
NEUROSCIENCE LETTERS (2000)
Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure
WC Wolf et al.
KIDNEY INTERNATIONAL (2000)
Fluorescent microplate assay for cancer cell-associated cathepsin B
KI Hulkower et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)
Cells producing cathepsins D, B, and L in human breast carcinoma and their association with prognosis
TT Lah et al.
HUMAN PATHOLOGY (2000)