Related references
Note: Only part of the references are listed.Structure based virtual screening, 3D-QSAR, molecular dynamics and ADMET studies for selection of natural inhibitors against structural and non-structural targets of Chikungunya
Jaykant Vora et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2019)
Multiple roles of the non-structural protein 3 (nsP3) alphavirus unique domain (AUD) during Chikungunya virus genome replication and transcription
Yanni Gao et al.
PLOS PATHOGENS (2019)
Marine natural products
Anthony R. Carroll et al.
NATURAL PRODUCT REPORTS (2019)
Current landscape and future prospects of antiviral drugs derived from microbial products
Naoki Takizawa et al.
JOURNAL OF ANTIBIOTICS (2018)
Molecular Docking Studies to Explore Potential Binding Pockets and Inhibitors for Chikungunya Virus Envelope Glycoproteins
Phuong T. V. Nguyen et al.
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES (2018)
Identification of small molecule inhibitors of the Chikungunya virus nsP1 RNA capping enzyme
Kristen M. Feibelman et al.
ANTIVIRAL RESEARCH (2018)
Deciphering the potential of baicalin as an antiviral agent for Chikungunya virus infection
Adrian Oo et al.
ANTIVIRAL RESEARCH (2018)
Chikungunya virus inhibition by peptidomimetic inhibitors targeting virus-specific cysteine protease
Harvijay Singh et al.
BIOCHIMIE (2018)
Design, synthesis and evaluation against Chikungunya virus of novel small-molecule antiviral agents
Roberta Tardugno et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Differences in Transmission and Disease Severity Between 2 Successive Waves of Chikungunya
Aubree Gordon et al.
CLINICAL INFECTIOUS DISEASES (2018)
A bibliometric review of drug repurposing
Nancy C. Baker et al.
DRUG DISCOVERY TODAY (2018)
Rational modifications on a benzylidene-acrylohydrazide antiviral scaffold, synthesis and evaluation of bioactivity against Chikungunya virus
Gilda Giancotti et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Experimental risk assessment for chikungunya virus transmission based on vector competence, distribution and temperature suitability in Europe, 2018
Anna Heitmann et al.
EUROSURVEILLANCE (2018)
Treatment of chikungunya musculoskeletal disorders: a systematic review
Lusiele Guaraldo et al.
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2018)
Crystal structure of chikungunya virus nsP2 cysteine protease reveals a putative flexible loop blocking its active site
Manju Narwal et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)
DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability
Carlos H. M. Rodrigues et al.
NUCLEIC ACIDS RESEARCH (2018)
Seroepidemiology of Chikungunya Virus Among Febrile Patients in Eight Health Facilities in Central and Northern Mozambique, 2015-2016
Virgilio S. Antonio et al.
VECTOR-BORNE AND ZOONOTIC DISEASES (2018)
Structure-function insights into chikungunya virus capsid protein: Small molecules targeting capsid hydrophobic pocket
Rajesh Sharma et al.
VIROLOGY (2018)
Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses
Jan Haviernik et al.
VIRUSES-BASEL (2018)
Current Strategies for Inhibition of Chikungunya Infection
Bharat Bhusan Subudhi et al.
VIRUSES-BASEL (2018)
Nonstructural Proteins of AlphavirusPotential Targets for Drug Development
Farhana Abu Bakar et al.
VIRUSES-BASEL (2018)
Quantum Chemical Approaches in Structure-Based Virtual Screening and Lead Optimization
Claudio N. Cavasotto et al.
FRONTIERS IN CHEMISTRY (2018)
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
Raimunda S. S. Azevedo et al.
SCIENTIFIC REPORTS (2018)
Development of nsP2 protease based cell free high throughput screening assay for evaluation of inhibitors against emerging Chikungunya virus
Amrita Saha et al.
SCIENTIFIC REPORTS (2018)
Micafungin is a novel anti-viral agent of chikungunya virus through multiple mechanisms
Yi-Jung Ho et al.
ANTIVIRAL RESEARCH (2018)
ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication
Rachy Abraham et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Reply to Simon et al. on The neurological complications of chikungunya virus: A systematic review
Ravi Mehta et al.
REVIEWS IN MEDICAL VIROLOGY (2018)
Conserved motifs in the hypervariable domain of chikungunya virus nsP3 required for transmission by Aedes aegypti mosquitoes
Giel P. Goertz et al.
PLOS NEGLECTED TROPICAL DISEASES (2018)
Conformer and pharmacophore based identification of peptidomimetic inhibitors of chikungunya virus nsP2 protease
Sonali Dhindwal et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2017)
Global expansion of chikungunya virus: mapping the 64-year history
Braira Wahid et al.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2017)
Chikungunya virus: epidemiology, replication, disease mechanisms, and prospective intervention strategies
Laurie A. Silva et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Mutations in the E2 Glycoprotein and the 3′ Untranslated Region Enhance Chikungunya Virus Virulence in Mice
David W. Hawman et al.
JOURNAL OF VIROLOGY (2017)
An update on Zika virus infection
David Baud et al.
LANCET (2017)
Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen
Felicity J. Burt et al.
LANCET INFECTIOUS DISEASES (2017)
Potential Antivirals: Natural Products Targeting Replication Enzymes of Dengue and Chikungunya Viruses
Ana Flavia Costa da Silveira Oliveira et al.
MOLECULES (2017)
Structural studies of Chikungunya virus maturation
Moh Lan Yap et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Alphavirus polymerase and RNA replication
Maija K. Pietla et al.
VIRUS RESEARCH (2017)
Chikungunya Virus: Pathophysiology, Mechanism, and Modeling
Vaishnavi K. Ganesan et al.
VIRUSES-BASEL (2017)
Arboviruses emerging in Brazil: challenges for clinic and implications for public health
Maria Rita Donalisio et al.
REVISTA DE SAUDE PUBLICA (2017)
Mutation of the N-Terminal Region of Chikungunya Virus Capsid Protein: Implications for Vaccine Design
Adam Taylor et al.
MBIO (2017)
Promiscuous viruses-how do viruses survive multiple unrelated hosts?
Gregory D. Ebel
CURRENT OPINION IN VIROLOGY (2017)
Chikungunya virus infections: time to act, time to treat
Rana Abdelnabi et al.
CURRENT OPINION IN VIROLOGY (2017)
Marine alkaloid oroidin analogues with antiviral potential: A novel class of synthetic compounds targeting the cellular chaperone Hsp90
Katja-Emilia Lillsunde et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2017)
Evaluation of antiviral activity of piperazine against Chikungunya virus targeting hydrophobic pocket of alphavirus capsid protein
Megha Aggarwal et al.
ANTIVIRAL RESEARCH (2017)
Chikungunya virus nsP4 RNA-dependent RNA polymerase core domain displays detergent-sensitive primer extension and terminal adenylyltransferase activities
Ming Wei Chen et al.
ANTIVIRAL RESEARCH (2017)
Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding
Bryan C. Mounce et al.
ANTIVIRAL RESEARCH (2017)
Structure-function relationship of Chikungunya nsP2 protease: A comparative study with papain
Chandrasekaran Ramakrishnan et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2017)
Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication
Maria Scuotto et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
Spectral characterisation, antiviral activities, in silico ADMET and molecular docking of the compounds isolated from Tectona grandis to chikungunya virus
K. Sangeetha et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Chikungunya Infection: a Global Public Health Menace
A. J. Mathew et al.
CURRENT ALLERGY AND ASTHMA REPORTS (2017)
Molecular modeling and docking study to elucidate novel chikungunya virus nsP2 protease inhibitors
A Bissoyi et al.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
Antiviral activity of selected flavonoids against Chikungunya virus
Rafidah Lani et al.
ANTIVIRAL RESEARCH (2016)
Alphavirus protease inhibitors from natural sources: A homology modeling and molecular docking investigation
Kendall G. Byler et al.
COMPUTATIONAL BIOLOGY AND CHEMISTRY (2016)
Correlation of phylogenetic clade diversification and in vitro infectivity differences among Cosmopolitan genotype strains of Chikungunya virus
Rachy Abraham et al.
INFECTION GENETICS AND EVOLUTION (2016)
Inhibition of chikungunya virus by picolinate that targets viral capsid protein
Rajesh Sharma et al.
VIROLOGY (2016)
Two novel epistatic mutations (E1:K211E and E2:V264A) in structural proteins of Chikungunya virus enhance fitness in Aedes aegypti
Ankita Agarwal et al.
VIROLOGY (2016)
Inhibition of chikungunya virus replication by hesperetin and naringenin
Azin Ahmadi et al.
RSC ADVANCES (2016)
Inhibition of Chikungunya Virus Replication by 1-[(2-Methylbenzimidazol-1-yl) Methyl]-2-Oxo-Indolin-3-ylidene] Amino] Thiourea(MBZM-N-IBT)
Priyadarsee Mishra et al.
SCIENTIFIC REPORTS (2016)
Chikungunya: an unexpected emergence in Europe
Fadila Amraoui et al.
CURRENT OPINION IN VIROLOGY (2016)
In silico study on anti-Chikungunya virus activity of hesperetin
Adrian Oo et al.
PEERJ (2016)
The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection
L. Delang et al.
SCIENTIFIC REPORTS (2016)
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
Valentina Cappello et al.
SCIENTIFIC REPORTS (2016)
Dengue, Zika and Chikungunya: Emerging Arboviruses in the New World
Jessica Patterson et al.
WESTERN JOURNAL OF EMERGENCY MEDICINE (2016)
Chikungunya: Evolutionary history and recent epidemic spread
Scott C. Weaver et al.
ANTIVIRAL RESEARCH (2015)
Discovery of Novel Peptidomimetics as Irreversible CHIKV NsP2 Protease Inhibitors Using Quantum Mechanical-Based Ligand Descriptors
Eman M. El-labbad et al.
CHEMICAL BIOLOGY & DRUG DESIGN (2015)
Thiazolidone derivatives as inhibitors of chikungunya virus
Surender Singh Jadav et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Alphavirus RNA synthesis and non-structural protein functions
Jonathan C. Rupp et al.
JOURNAL OF GENERAL VIROLOGY (2015)
Identification of chikungunya virus nsP2 protease inhibitors using structure-base approaches
Phuong T. V. Nguyen et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2015)
Reaching beyond HIV/HCV: nelfinavir as a potential starting point for broad-spectrum protease inhibitors against dengue and chikungunya virus
Soumendranath Bhakat et al.
RSC ADVANCES (2015)
Activity of andrographolide against chikungunya virus infection
Phitchayapak Wintachai et al.
SCIENTIFIC REPORTS (2015)
Kinetic characterization of trans-proteolytic activity of Chikungunya virus capsid protease and development of a FRET-based HTS assay
Megha Aggarwal et al.
SCIENTIFIC REPORTS (2015)
Structural basis for complementary and alternative medicine: Phytochemical interaction with non-structural protein 2 protease-a reverse engineering strategy
G. Koushik Kumar et al.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE (2015)
Seaweeds with anti-herpes simplex virus type 1 activity
Caroline de Souza Barros et al.
JOURNAL OF APPLIED PHYCOLOGY (2015)
A Combination of Doxycycline and Ribavirin Alleviated Chikungunya Infection
Hussin A. Rothan et al.
PLOS ONE (2015)
Suramin Inhibits Chikungunya Virus Entry and Transmission
Yi-Jung Ho et al.
PLOS ONE (2015)
Structure-activity relationship study of arbidol derivatives as inhibitors of chikungunya virus replication
Antonia Di Mola et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2014)
Discovery of in silico hits targeting the nsP3 macro domain of chikungunya virus
Phuong T. V. Nguyen et al.
JOURNAL OF MOLECULAR MODELING (2014)
A Single-Amino-Acid Polymorphism in Chikungunya Virus E2 Glycoprotein Influences Glycosaminoglycan Utilization
Laurie A. Silva et al.
JOURNAL OF VIROLOGY (2014)
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus
Marcella Bassetto et al.
ANTIVIRAL RESEARCH (2013)
Chikungunya fever: Epidemiology, clinical syndrome, pathogenesis and therapy
Simon-Djamel Thiberville et al.
ANTIVIRAL RESEARCH (2013)
Genetic characterization of E2 region of Chikungunya virus circulating in Odisha, Eastern India from 2010 to 2011
Abhipsa Sahu et al.
INFECTION GENETICS AND EVOLUTION (2013)
Identification of structural motifs in the E2 glycoprotein of Chikungunya involved in virus-host interaction
J. Asnet Mary et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2013)
Structure based design towards the identification of novel binding sites and inhibitors for the chikungunya virus envelope proteins
Adel A. Rashad et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2013)
The C-Terminal Domain of Chikungunya Virus nsP2 Independently Governs Viral RNA Replication, Cytopathicity, and Inhibition of Interferon Signaling
Jelke J. Fros et al.
JOURNAL OF VIROLOGY (2013)
S-Adenosyl-Methionine-Dependent Methyltransferases: Highly Versatile Enzymes in Biocatalysis, Biosynthesis and Other Biotechnological Applications
Anna-Winona Struck et al.
CHEMBIOCHEM (2012)
Homology modeling, molecular dynamics, e-pharmacophore mapping and docking study of Chikungunya virus nsP2 protease
Kh. Dhanachandra Singh et al.
JOURNAL OF MOLECULAR MODELING (2012)
Arthritogenic alphaviruses-an overview
Andreas Suhrbier et al.
NATURE REVIEWS RHEUMATOLOGY (2012)
Structural and functional insights into alphavirus polyprotein processing and pathogenesis
Gyehwa Shin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
PDZ domains and their binding partners: structure, specificity, and modification
Ho-Jin Lee et al.
CELL COMMUNICATION AND SIGNALING (2010)
Molecular insight into the specific binding of ADP-ribose to the nsP3 macro domains of chikungunya and venezuelan equine encephalitis viruses: Molecular dynamics simulations and free energy calculations
Thanyada Rungrotmongkol et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2010)
Functional dissection of the alphavirus capsid protease: sequence requirements for activity
Saijo Thomas et al.
VIROLOGY JOURNAL (2010)
QM/MM Calculations in Drug Discovery: A Useful Method for Studying Binding Phenomena?
M. Paul Gleeson et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2009)
The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket
Helene Malet et al.
JOURNAL OF VIROLOGY (2009)
Epistatic Roles of E2 Glycoprotein Mutations in Adaption of Chikungunya Virus to Aedes Albopictus and Ae. Aegypti Mosquitoes
Konstantin A. Tsetsarkin et al.
PLOS ONE (2009)
Replication cycle of chikungunya: A re-emerging arbovirus
Maxime Solignat et al.
VIROLOGY (2009)
A single mutation in chikungunya virus affects vector specificity and epidemic potential
Konstantin A. Tsetsarkin et al.
PLOS PATHOGENS (2007)