4.5 Review

Clinical significance of chemokine receptor antagonists

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Improving maraviroc oral bioavailability by formation of solid drug nanoparticles

Alison C. Savage et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

Article Pharmacology & Pharmacy

Towards a Maraviroc long-acting injectable nanoformulation

Lee M. Tatham et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2019)

Article Biochemistry & Molecular Biology

CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury

Mary T. Joy et al.

Article Oncology

Mycosis Fungoides and Sezary Syndrome: An Update

Cecilia Larocca et al.

HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA (2019)

Article Infectious Diseases

Efficacy and safety of long-term maraviroc use in a heterogeneous group of HIV-infected patients: A retrospective cohort study

J. M. Weehuizen et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2019)

Review Biochemistry & Molecular Biology

CCR5/CXCR4 Dual Antagonism for the Improvement of HIV Infection Therapy

Fedora Grande et al.

MOLECULES (2019)

Article Multidisciplinary Sciences

HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation

Ravindra K. Gupta et al.

NATURE (2019)

Review Biotechnology & Applied Microbiology

Mogamulizumab: a new tool for management of cutaneous T-cell lymphoma

Thomas A. Ollila et al.

ONCOTARGETS AND THERAPY (2019)

Review Cell Biology

Involvement of CXCR4 in Normal and Abnormal Development

Nanako Kawaguchi et al.

CELLS (2019)

Review Biochemistry & Molecular Biology

Potential roles and targeted therapy of the CXCLs/CXCR2 axis in cancer and inflammatory diseases

Yuan Cheng et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)

Article Oncology

FDA Approval Summary: Mogamulizumab-kpkc for Mycosis Fungoides and Sezary Syndrome

Yvette L. Kasamon et al.

CLINICAL CANCER RESEARCH (2019)

Article Pharmacology & Pharmacy

A drug safety evaluation of mogamulizumab for the treatment of cutaneous T-Cell lymphoma

Salma Afifi et al.

EXPERT OPINION ON DRUG SAFETY (2019)

Article Oncology

CCR5 status and metastatic progression in colorectal cancer

Meggy Suarez-Carmona et al.

ONCOIMMUNOLOGY (2019)

Review Biochemistry & Molecular Biology

Dual CCR5/CCR2 targeting: opportunities for the cure of complex disorders

Laura Fantuzzi et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

Article Biochemistry & Molecular Biology

The CXCR4-CXCL12-Axis Is of Prognostic Relevance in DLBCL and Its Antagonists Exert Pro-Apoptotic Effects In Vitro

Katrin Pansy et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Review Immunology

WHIM syndrome: Immunopathogenesis, treatment and cure strategies

David H. McDermott et al.

IMMUNOLOGICAL REVIEWS (2019)

Review Biochemistry & Molecular Biology

Adaptive Immunodeficiency in WHIM Syndrome

Shamik Majumdar et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Multidisciplinary Sciences

Structural basis of coreceptor recognition by HIV-1 envelope spike

Md Munan Shaik et al.

NATURE (2019)

Article Medicine, General & Internal

Plerixafor for the Treatment of WHIM Syndrome

David H. McDermott et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Infectious Diseases

Week 96 results of the randomized, multicentre Maraviroc Switch (MARCH) study

S. L. Pett et al.

HIV MEDICINE (2018)

Article Biochemistry & Molecular Biology

Pharmacogenomics of GPCR Drug Targets

Alexander S. Hauser et al.

Editorial Material Pharmacology & Pharmacy

Cenicriviroc for the treatment of non-alcoholic steatohepatitis and liver fibrosis

Frank Tacke

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2018)

Article Biochemistry & Molecular Biology

A guide to chemokines and their receptors

Catherine E. Hughes et al.

FEBS JOURNAL (2018)

Editorial Material Hematology

Hematopoietic stem cell mobilization with plerixafor in sickle cell disease

Matthew M. Hsieh et al.

HAEMATOLOGICA (2018)

Article Immunology

Improved Cognitive Performance and Reduced Monocyte Activation in Virally Suppressed Chronic HIV After Dual CCR2 and CCR5 Antagonism

Michelle L. D'Antoni et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2018)

Review Gastroenterology & Hepatology

Chemokines and Chemokine Receptors as Therapeutic Targets in Inflammatory Bowel Disease; Pitfalls and Promise

Palak J. Trivedi et al.

JOURNAL OF CROHNS & COLITIS (2018)

Article Gastroenterology & Hepatology

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

Maria Eugenia Guicciardi et al.

JOURNAL OF HEPATOLOGY (2018)

Article Medicine, General & Internal

Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy

Tomoo Sato et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Immunology

The return of PRO 140, a CCR5-directed mAb

Melanie A. Thompson

CURRENT OPINION IN HIV AND AIDS (2018)

Editorial Material Hematology

Hematopoietic stem cell mobilization with plerixafor in sickle cell disease

Matthew M. Hsieh et al.

HAEMATOLOGICA (2018)

Editorial Material Chemistry, Medicinal

CCR4 Antagonists Inhibit Treg Trafficking into the Tumor Microenvironment

John M. Ketcham et al.

ACS MEDICINAL CHEMISTRY LETTERS (2018)

Article Biochemistry & Molecular Biology

Biased antagonism of CXCR4 avoids antagonist tolerance

Ben Hitchinson et al.

SCIENCE SIGNALING (2018)

Review Hematology

The evolution of stem-cell transplantation in multiple myeloma

Sarakshi Mahajan et al.

THERAPEUTIC ADVANCES IN HEMATOLOGY (2018)

Review Biochemistry & Molecular Biology

Pharmacogenetic considerations for HIV treatment in different ethnicities: an update

M. Neary et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2017)

Article Chemistry, Medicinal

Structural Analysis of Chemokine Receptor-Ligand Interactions

Marta Arimont et al.

JOURNAL OF MEDICINAL CHEMISTRY (2017)

Review Immunology

Beyond Chemoattraction: Multifunctionality of Chemokine Receptors in Leukocytes

Pilar Lopez-Cotarelo et al.

TRENDS IN IMMUNOLOGY (2017)

Review Medicine, Research & Experimental

Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases

Helen Ha et al.

THERANOSTICS (2017)

Article Oncology

A Multicenter Retrospective Study of Mogamulizumab Efficacy in Adult T-Cell Leukemia/Lymphoma

Satoshi Iyama et al.

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2017)

Article Medicine, Research & Experimental

Pharmacokinetics, Safety, and CCR2/CCR5 Antagonist Activityof Cenicriviroc in Participants With Mild or Moderate Hepatic Impairment

E. Lefebvre et al.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2016)

Review Hematology

Plerixafor for stem cell mobilization: the current status

Yavuz M. Bilgin et al.

CURRENT OPINION IN HEMATOLOGY (2016)

Article Multidisciplinary Sciences

Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

Yi Zheng et al.

NATURE (2016)

Review Clinical Neurology

CCR5 blockade for neuroinflammatory diseases - beyond control of HIV

Guillaume Martin-Blondel et al.

NATURE REVIEWS NEUROLOGY (2016)

Article Multidisciplinary Sciences

Maraviroc Reduces Arterial Stiffness in PI-Treated HIV-infected Patients

Stefania Piconi et al.

SCIENTIFIC REPORTS (2016)

Article Pharmacology & Pharmacy

Chemokine receptors as therapeutic targets: Why aren't there more drugs?

Roberto Solari et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2015)

Article Genetics & Heredity

CXC chemokine ligand 12 (CXCL12) and its receptor CXCR4

Takashi Nagasawa

JOURNAL OF MOLECULAR MEDICINE-JMM (2014)

Article Pharmacology & Pharmacy

CYP3A5 Genotype Impacts Maraviroc Concentrations in Healthy Volunteers

Yanhui Lu et al.

DRUG METABOLISM AND DISPOSITION (2014)

Article Chemistry, Medicinal

Structure-Based Development of Antagonists for Chemokine Receptor CXCR4

Chongqian Zhang et al.

Current Computer-Aided Drug Design (2013)

Review Oncology

A review on CXCR4/CXCL12 axis in oncology: No place to hide

Urszula M. Domanska et al.

EUROPEAN JOURNAL OF CANCER (2013)

Article Multidisciplinary Sciences

Structure of the CCR5 Chemokine Receptor-HIV Entry Inhibitor Maraviroc Complex

Qiuxiang Tan et al.

SCIENCE (2013)

Review Immunology

The Chemokine Superfamily Revisited

Albert Zlotnik et al.

IMMUNITY (2012)

Article Immunology

Overcoming hurdles in developing successful drugs targeting chemokine receptors

Thomas J. Schall et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Article Hematology

A Pharmacokinetic Study of Plerixafor in Subjects with Varying Degrees of Renal Impairment

Ronald MacFarland et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2010)

Article Infectious Diseases

Primary resistance to maraviroc in a large set of R5-V3 viral sequences from HIV-1-infected patients

Eduardo Seclen et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2010)

Article Infectious Diseases

The Monoclonal CCR5 Antibody PRO-140: The Promise of Once-Weekly HIV Therapy

Allan R. Tenorio

Current HIV/AIDS Reports (2010)

Article Hematology

Pharmacokinetics and Pharmacodynamics of Plerixafor in Patients with Non-Hodgkin Lymphoma and Multiple Myeloma

Douglas A. Stewart et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2009)

Article Pharmacology & Pharmacy

Plerixafor In Patients with Non-Hodgkin's Lymphoma or Multiple Myeloma

Antona J. Wagstaff

DRUGS (2009)

Article Immunology

Maraviroc Concentrates in the Cervicovaginal Fluid and Vaginal Tissue of HIV-Negative Women

Julie B. Dumond et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2009)

Review Biotechnology & Applied Microbiology

OPINION Chemokine receptor antagonists: overcoming developmental hurdles

Richard Horuk

NATURE REVIEWS DRUG DISCOVERY (2009)

Article Pharmacology & Pharmacy

Maraviroc:: in vitro assessment of drug-drug interaction potential

Ruth Hyland et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2008)

Article Pharmacology & Pharmacy

Assessment of the absorption, metabolism and absolute bioavailability of maraviroc in healthy male subjects

Samantha Abel et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2008)

Article Medicine, General & Internal

Subgroup analyses of Maraviroc in previously treated R5 HIV-1 infection

Gerd Faetkenheuer et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Medicine, General & Internal

Maraviroc for previously treated patients with R5 HIV-1 infection

Roy M. Gulick et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Microbiology

Hepatotoxicity observed in clinical trials of aplaviroc (GW873140)

W. G. Nichols et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2008)

Review Medicine, General & Internal

Mechanisms of disease - The many roles of chemokines and chemokine receptors in inflammation

IF Charo et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Biochemistry & Molecular Biology

The geographic spread of the CCR5 Δ32 HIV-resistance allele

J Novembre et al.

PLOS BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1

G Fätkenheuer et al.

NATURE MEDICINE (2005)

Article Pharmacology & Pharmacy

A pharmacokinetic-pharmacodynamic model for the mobilization of CD34+ hematopoietic progenitor cells by AMD3100

NA Lack et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2005)

Article Pharmacology & Pharmacy

Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV

DK Walker et al.

DRUG METABOLISM AND DISPOSITION (2005)

Article Biochemistry & Molecular Biology

Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor - Transfer of binding site to the CXCR3 receptor

MM Rosenkilde et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Immunology

Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection

CW Hendrix et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2004)

Article Biotechnology & Applied Microbiology

The bicyclam AMD3 100 story

E De Clercq

NATURE REVIEWS DRUG DISCOVERY (2003)