Torpedo maculopathy: A case series - insights into basic pathology

Torpedo maculopathy is a benign retinal disorder whose pathophysiological origins are currently poorly understood. A number of theories have been postulated, with stable developmental anomalies of the retinal pigment epithelium taking the forefront. Four clinical cases are outlined of patients with macular torpedo lesions, with differing clinical presentation. In all four cases, this reveals very thin retinal pigment epithelium and outer retina associated with the lesion. In a single case, the oldest patient of the group, there is the additional finding of subretinal and intraretinal fluid accumulation. The contrast between this case and the other cases suggests that while initially this benign pathology might start with structurally normal retina with no fluid accumulation, dysgenetic changes in the retinal pigment epithelium might lead to secondary accumulation of fluid over time. Whether indeed this disorder might be progressive in nature, or whether in fact it is a static, non-progressive developmental abnormality as formerly thought, requires further elucidation.

Automated summary

Torpedo maculopathy is a benign retinal disorder with poorly understood pathophysiological origins. The study outlines four clinical cases, with one showing additional findings of fluid accumulation, suggesting that dysgenetic changes in the retinal pigment epithelium may lead to secondary fluid accumulation over time. Whether this disorder is progressive or static in nature requires further clarification.