Journal
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
Volume 188, Issue -, Pages -Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ecoenv.2019.109837
Keywords
Antibiotic resistance genes; Drinking water; National-scale investigation; City type
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Funding
- National Natural Science Foundation of China [41831287]
- Tianjin Municipal Science and Technology BureauB of China [19JCYBJC23200, 18YFZCSF00740]
- Fundamental Research Funds for the Central Universities of China
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Drinking water samples were collected from 71 cities, including 28 provincial capital cities or municipalities, 20 prefecture cities and 23 counties, of 31 provincial-level administrative regions in China from July to August in 2017. Futhermore, 24 Antibiotic Resistance Genes (ARGs), 16S rRNA and 2 integrase genes were quantified by qPCR to investigate the pollution degree of ARGs. The results revealed that the 16S ranged from 105 108 copies/100 mL in the drinking water, and its treatment process could effectively remove bacteria. Moreover, sulfonamides-ARGs were the most prevalent ARGs in the drinking water of China, and the abundance of bla(TEM) ranked top five in all cities among the selected ARGs, indicating that the pollution condition of the genes should be aroused more attention. The data of qPCR and correlation analyses indicated that intl1 played a more crucial role than intl2 in the propagation of ARGs in the drinking water. Additionally, the pollution degree of ARGs among different city types showed no significant difference.
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