4.5 Review

Addressing variability in iPSC-derived models of human disease: guidelines to promote reproducibility

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures

Konstantin Zaitsev et al.

NATURE COMMUNICATIONS (2019)

Meeting Abstract Clinical Neurology

Olfactory neurons as surrogate tissue to investi-gate disorders of the brain

J. Unterholzner et al.

EUROPEAN NEUROPSYCHOPHARMACOLOGY (2019)

Correction Genetics & Heredity

Challenges in unsupervised clustering of single-cell RNA-seq data (vol 20, pg 273, 2019)

Vladimir Yu Kiselev et al.

NATURE REVIEWS GENETICS (2019)

Article Multidisciplinary Sciences

Bulk tissue cell type deconvolution with multi-subject single-cell expression reference

Xuran Wang et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

Impact of regulatory variation across human iPSCs and differentiated cells

Nicholas E. Banovich et al.

GENOME RESEARCH (2018)

Article Genetics & Heredity

Molecular and functional variation in iPSC-derived sensory neurons

Jeremy Schwartzentruber et al.

NATURE GENETICS (2018)

Article Biochemistry & Molecular Biology

Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse

Cynthia L. Smith et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biochemistry & Molecular Biology

Sorting cells alters their redox state and cellular metabolome

Elizabeth M. Llufrio et al.

REDOX BIOLOGY (2018)

Article Multidisciplinary Sciences

Need for high-resolution Genetic Analysis in iPSC: Results and Lessons from the ForIPS Consortium

Bernt Popp et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes

Jing Zhao et al.

HUMAN MOLECULAR GENETICS (2017)

Article Multidisciplinary Sciences

Common genetic variation drives molecular heterogeneity in human iPSCs

Helena Kilpinen et al.

NATURE (2017)

Article Multidisciplinary Sciences

Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations

Florian T. Merkle et al.

NATURE (2017)

Article Biochemistry & Molecular Biology

Gene expression variability and the analysis of large-scale RNA-seq studies with the MDSeq

Di Ran et al.

NUCLEIC ACIDS RESEARCH (2017)

Article Medicine, Research & Experimental

iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases

Ethan W. Hollingsworth et al.

EMBO MOLECULAR MEDICINE (2017)

Article Biochemistry & Molecular Biology

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

Gioele La Manno et al.

Review Pharmacology & Pharmacy

Organoid-on-a-chip and body-on-a-chip systems for drug screening and disease modeling

Aleksander Skardal et al.

DRUG DISCOVERY TODAY (2016)

Article Biochemical Research Methods

A high-content platform to characterise human induced pluripotent stem cell lines

Andreas Leha et al.

METHODS (2016)

Article Biochemistry & Molecular Biology

Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology

C. Bardy et al.

MOLECULAR PSYCHIATRY (2016)

Article Biotechnology & Applied Microbiology

Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells

Florian Buettner et al.

NATURE BIOTECHNOLOGY (2015)

Article Genetics & Heredity

Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature

Samantha M. Thomas et al.

PLOS GENETICS (2015)

Article Biochemistry & Molecular Biology

Long-term electrophysiological activity and pharmacological response of a human induced pluripotent stem cell-derived neuron and astrocyte co-culture

A. Odawara et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Article Biochemistry & Molecular Biology

Assessing Kinetics from Fixed Cells Reveals Activation of the Mitotic Entry Network at the S/G2 Transition

Karen Akopyan et al.

MOLECULAR CELL (2014)

Article Developmental Biology

Gain of 20q11.21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL

H. T. Nguyen et al.

MOLECULAR HUMAN REPRODUCTION (2014)

Article Multidisciplinary Sciences

A three-dimensional human neural cell culture model of Alzheimer's disease

Se Hoon Choi et al.

NATURE (2014)

Article Biotechnology & Applied Microbiology

Normalization of RNA-seq data using factor analysis of control genes or samples

Davide Risso et al.

NATURE BIOTECHNOLOGY (2014)

Article Biotechnology & Applied Microbiology

Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories

Peter A. C. 't Hoen et al.

NATURE BIOTECHNOLOGY (2013)

Article Multidisciplinary Sciences

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong et al.

SCIENCE (2013)

Article Cell & Tissue Engineering

Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling

Shila Mekhoubad et al.

CELL STEM CELL (2012)

Review Biochemistry & Molecular Biology

Epigenetics of Pluripotent Cells

S. P. Medvedev et al.

ACTA NATURAE (2012)

Article Multidisciplinary Sciences

Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome

Guang-Hui Liu et al.

NATURE (2011)

Article Multidisciplinary Sciences

Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

Bao-Yang Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)