Journal
DEVELOPMENTAL CELL
Volume 52, Issue 3, Pages 257-258Publisher
CELL PRESS
DOI: 10.1016/j.devcel.2020.01.021
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Chromosomes containing two centromeres (dicentrics) trigger chromosome instability that is avoided by the enigmatic process of centromere inactivation. In this issue of Developmental Cell, Palladino et al. (2020) combine in vivo chromosome engineering and Drosophila genetics to assess consequences of de novo centromere formation and clarify models of centromere inactivation.
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