Journal
DEVELOPMENT
Volume 147, Issue 1, Pages -Publisher
COMPANY BIOLOGISTS LTD
DOI: 10.1242/dev.181081
Keywords
Cell fates; Cell lineages; Developmental plasticity; Emerging model systems; Phylogeny; Spiral cleavage
Categories
Funding
- European Research Council [801669]
- Okinawa Institute of Science and Technology
- Japan Society for the Promotion of Science Kakenhi Grant
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Snails, earthworms and flatworms are remarkably different animals, but they all exhibit a very similar mode of early embryogenesis: spiral cleavage. This is one of the most widespread developmental programs in animals, probably ancestral to almost half of the animal phyla, and therefore its study is essential for understanding animal development and evolution. However, our knowledge of spiral cleavage is still in its infancy. Recent technical and conceptual advances, such as the establishment of genome editing and improved phylogenetic resolution, are paving the way for a fresher and deeper look into this fascinating early cleavage mode.
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