Journal
CURRENT TREATMENT OPTIONS IN ONCOLOGY
Volume 21, Issue 1, Pages -Publisher
SPRINGER
DOI: 10.1007/s11864-019-0696-4
Keywords
Sinonasal cancer; Sinonasal malignancies; Multimodal therapy; Head and neck cancer; Systemic therapy; Chemotherapy
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Opinion statement Sinonasal malignancies pose a significant challenge in management due to their low incidence, biologic diversity, and significant symptom burden. Even though surgery remains the primary therapeutic modality, a multi-modality approach has been shown to benefit a significant proportion of patients and its success depends largely on stage and histologic type. Non-surgical approaches such as novel radiation approaches as well as intensification with systemic therapy hold promise in altering the organ preservation rate as well as overall survival for patients. Practice changing randomized trials to test these novel modalities are overdue and desperately needed.
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