4.5 Article

Nutrient homeostasis - translating internal states to behavior

Journal

CURRENT OPINION IN NEUROBIOLOGY
Volume 60, Issue -, Pages 67-75

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.conb.2019.10.004

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Funding

  1. Lisbon Regional Operational Programme (POR) by FCT -Foundation for Science and Tecnologia, I.P.
  2. European Regional Development Fund (FEDER) [02/SAICT/300081/2017]
  3. Fundacao filial grant [279/16]
  4. la Caixa Foundation grant [HR17-00539]
  5. DFG Research Fellowship [MU 4116/1-1]
  6. Fundacao Bial grant [279/16]
  7. FCT [PD/BD/114277/2016]
  8. Champalimaud Foundation
  9. Fundação para a Ciência e a Tecnologia [PD/BD/114277/2016] Funding Source: FCT

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Behavioral neuroscience aims to describe a causal relationship between neuronal processes and behavior. Animals' ever-changing physiological needs alter their internal states. Internal states then alter neuronal processes to adapt the behavior of the animal enabling it to meet its needs. Here, we describe nutrient-specific appetites as an attractive framework to study how internal states shape complex neuronal processes and resulting behavioral outcomes. Understanding how neurons detect nutrient states and how these are integrated at the level of neuronal circuits will provide a multilevel description of the mechanisms underlying complex feeding and foraging decisions.

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