The relationship between host circadian rhythms and intestinal microbiota: A new cue to improve health by tea polyphenols

Under the control of the host circadian rhythms, intestinal microbiota undergoes dietary-dependent diurnal fluctuations in composition and function. In addition, microbiome plays a critical role in maintaining the host circadian rhythms and metabolic homeostasis. The interactions between host circadian rhythms and intestinal microbiota suggest that intervention with prebiotics or probiotic is a possible way to alleviate circadian rhythm misalignment and related metabolic diseases. This review discusses the circadian rhythm oscillations of gut flora, relationship between host circadian rhythms and microbiome and related effects on metabolism. The influence on circadian rhythms by the interactions between tea polyphenols (TP) and intestinal microbiota is highlighted.

Automated summary

The intestinal microbiota undergoes dietary-dependent fluctuations under the control of host circadian rhythms, playing a critical role in maintaining circadian rhythms and metabolic homeostasis. Interventions with prebiotics or probiotics may help alleviate circadian rhythm misalignment and related metabolic diseases. The interactions between tea polyphenols and intestinal microbiota can influence circadian rhythms, highlighting a potential area for further research.