Journal
CLINICAL INFECTIOUS DISEASES
Volume 71, Issue 7, Pages E195-E198Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa075
Keywords
influenza incidence; antigenic imprinting; cohort effect; age-specific analysis
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Funding
- Canadian Institutes of Health Research (CIHR) [367129]
- Social Sciences and Humanities Research Council of Canada scholarship
- European Research Council [716323]
- CIHR
- government of Ontario
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When H3N2 replaced H1N1 as the dominant influenza A subtype during the 2018-2019 season, the pattern of age-specific incidence shifted due to the lingering effects of antigenic imprinting. The characteristic shape that imprinting leaves on influenza susceptibility could foster important advances in understanding and predicting the epidemiology of influenza.
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