4.7 Editorial Material

Deep Sequencing Reveals Occult Mansonellosis Coinfections in Residents From the Brazilian Amazon Village of SAo Gabriel da Cachoeira

Journal

CLINICAL INFECTIOUS DISEASES
Volume 71, Issue 8, Pages 1990-1993

Publisher

OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciaa082

Keywords

Mansonella perstans; Mansonella ozzardi; mansonellosis; coinfections; Brazil

Funding

  1. Fundacao de Amparo a Pesquisa do Estado do Amazonas [062.00647/2014, 062.01282/2018, 002.00200/2019]
  2. Brazilian National Council for Scientific and Technological Development (CNPQ)

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Mansonella ozzardi and Mansonella perstans infections both cause mansonellosis but are usually treated differently. Using a real-time polymerase chain reaction assay and deep sequencing, we reveal the presence of mansonellosis coinfections that were undetectable by standard diagnostic methods. Our results confirm mansonellosis coinfections and have important implications for the disease's treatment and diagnosis.

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