Journal
CLINICAL INFECTIOUS DISEASES
Volume 71, Issue 3, Pages 664-666Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciz1097
Keywords
HCV; HBV; HCV; HBV coinfection; fibrosis progression; ERCHIVES
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Funding
- NIDDK NIH HHS [P30 DK120531] Funding Source: Medline
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For persons with baseline Fibrosis-4 1.46-3.25, cirrhosis incidence/1000 patient-years was 49.3 among hepatitis B virus (HBV)/hepatitis C virus (HCV) coinfected and 18.2 among HCV monoinfected (P = .03). Cirrhosis risk was numerically higher but statistically nonsignificant among HBV/HCV coinfected (hazards ratio [HR] 1.51; 95% confidence intervals [CI], .37-6.05) but lower among those who attained sustained virologic response (HR, .52; 95% CI, .42-.63).
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