Journal
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
Volume 19, Issue 5, Pages 876-884Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.cgh.2020.02.054
Keywords
SEER Program; Pancreatic Adenocarcinoma; PDAC; Prevalence
Categories
Funding
- Center for Gastrointestinal Development, Infection and Injury (National Institute of Diabetes and Digestive and Kidney Diseases) [P30 DK 56338]
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Pancreatic cancer is the seventh leading cause of cancer-related deaths worldwide with 432,242 related deaths in 2018. Research on risk factors is crucial for prevention, surveillance, and treatment of pancreatic cancer.
Pancreatic cancer is the seventh leading cause of cancerrelated deaths worldwide with 432,242 related deaths in 2018. Unlike other cancers, the incidence of pancreatic cancer continues to increase, with little improvement in survival rates. We review the epidemiologic features of pancreatic cancer, covering surveillance and early detection in high-risk persons. We summarize data on worldwide incidence and mortality and analyze the 1975-2016 data from 9 registries of the National Cancer Institute's Surveillance, Epidemiology, and End Results study, on the overall burden of pancreatic cancer as well as age-, sex-, and race-specific incidence, survival rates and trends. It is important to increase our knowledge of the worldwide and regional epidemiologic features of and risk factors for pancreatic cancer, to identify new approaches for prevention, surveillance, and treatment.
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