4.6 Article

Reductive Aromatization of Quinols with B2pin2 as Deoxidizing Agent

Journal

CHEMISTRY-AN ASIAN JOURNAL
Volume 15, Issue 7, Pages 1022-1024

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/asia.202000064

Keywords

reductive aromatization; boron; deoxygenation; quinols

Funding

  1. Natural Science Foundation of China [21801099] Funding Source: Medline
  2. Senior Talent Foundation of Jiangsu University [18JDG016, 13JDG062] Funding Source: Medline

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We have demonstrated B(2)pin(2) as superior deoxidizing agent for the reductive deoxygenation of quinol derivatives under basic conditions. A wide range of highly functionalized phenols were obtained in good yields including a complex drug molecule, which revealed the high functional group tolerance of this protocol.

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