Journal
CHEMISTRY-AN ASIAN JOURNAL
Volume 15, Issue 2, Pages 231-241Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/asia.201901380
Keywords
metal-free approach; organocatalysis; quinolines; synthetic methods
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Funding
- National Natural Science Foundation of China [NSF21532001, NSF21772075]
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As one of the most widely investigated compound skeleton, quinolines possess important medicinal and biological activities. As such, a great number of literatures, including reviews, have reported various methodologies to construct quinolines. Recently, organocatalyzed reactions have attracted the attention of organic chemists due to its being green because the reactions avoid the use of toxic metals. In this review, various distinctive contributions are surveyed with specific emphasis on organocatalyzed reactions for quinoline core constructions.
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