Journal
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
Volume 36, Issue 2, Pages 211-218Publisher
HIGHER EDUCATION PRESS
DOI: 10.1007/s40242-019-0038-x
Keywords
DNA nanotechnology; Self-assembly; DNA-protein conjugation; DNA-protein hybrid structure
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DNA is the genetic information carrier for most known living organisms on Earth, while proteins are the functional component that carry out most biological processes. Many natural machineries are DNA-protein hybrid complexes to cooperatively and efficiently conduct sophisticated biological tasks. It has drawn increasing interest to the research field to construct artificial DNA-protein hybrid structures towards a variety of applications including biological studies, nanofabrication, biomedical research, etc. In this regard, here in this report we reviewed the up-to-date progress on making DNA-protein hybrid structures, with a particular focus on DNA nanotechnology-enabled programmable assembly of DNA-protein hybrid structures.
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