Journal
CHEMICAL ENGINEERING JOURNAL
Volume 381, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.cej.2019.122665
Keywords
Carbon dots; Fluorescent probe; Lysosome targeting; pH sensitive; Imaging
Categories
Funding
- National Natural Science Foundation of China [51873023, 51522307]
- Talent Development Fund of Jilin Province
Ask authors/readers for more resources
The anomalous fluctuations of pH in lysosome will cause the disorder of normal activity of cells and even many diseases. Thus, developing a convenient strategy for tracking pH changes of lysosome is highly desired. Herein, carbon dots (CDs)-based fluorescent probe with lysosome-targeting function was fabricated. CDs can monitor pH changes in live cells and organisms, with the aid of confocal laser scanning microscope and noninvasive optical imaging system. The advantages of CDs including robust photostability, high pH sensitivity and selectivity, good reversibility and low toxicity render them a prominent candidate to investigate pH-associated physiological and pathological processes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available