Journal
CELL STEM CELL
Volume 26, Issue 2, Pages 136-137Publisher
CELL PRESS
DOI: 10.1016/j.stem.2020.01.011
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Funding
- NCATS NIH HHS [UH3 TR002142] Funding Source: Medline
- NHLBI NIH HHS [R01 HL138252] Funding Source: Medline
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Human induced pluripotent stem cells (hiPSCs) provide a potentially unlimited cell source for producing autologous tissue-engineered vascular grafts (TEVGs), which currently suffer from low mechanical strength. In this issue of Cell Stem Cell, Luo et al. (2020) describe optimized culture media and a mechanical stretching regimen to produce hiPSC-derived TEVGs with mechanical behavior similar to that of natural vessels.
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