Journal
CARBOHYDRATE POLYMERS
Volume 226, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2019.115307
Keywords
Polygonum Cillinerve; Polysaccharide; Glucan; Antioxidant activity
Categories
Funding
- National Natural Science Foundation of China [31772788]
- Youth Innovation Team of Shaanxi Universities
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In this study, Polygonum Cillinerve polysaccharide (PCP) was extracted, and characterized by high performance gel permeation chromatography, high performance liquid chromatography, fourier transform infrared spectroscopy, nuclear magnetic resonance and mass spectroscopy. The results showed that PCP was composed of glucose, it was alpha-D-glucan and the backbone of PCP was consisted of repeating units of (1 -> 4)-alpha-D-Glucose. In addition, the antioxidant potential of PCP was assessed in vitro. The results showed that PCP had strong hydroxyl radical scavenging ability, some DPPH scavenging ability and good reducing power. Moreover, the results of the enzyme-linked immunosorbent assays showed that PCP at 15.625-0.975 mu g/mL could significantly improve the level of superoxide dismutase and glutathione peroxidase, and could significantly decrease the level of myeloperoxidase, malondialdehyde and xanthine oxidase in macrophages. These results indicated that PCP could potentially be developed as a natural antioxidant.
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