Viscerotropic disease and acute uveitis following yellow fever vaccination: a case report

BackgroundYellow fever vaccine exists for over 80years and is considered to be relatively safe. However, in rare cases it can produce serious neurotropic and viscerotropic complications. We report a case of a patient who presented both viscerotropic and neurological manifestations after yellow fever vaccination.Case presentationWe describe the case of a 37years old man who developed after the yellow fever vaccination a yellow fever vaccine-associated viscerotropic disease followed by acute uveitis. Prolonged detection of yellow fever RNA in blood and urine was consistent with yellow fever vaccine-associated adverse event. The final outcome was good, although with persistent fatigue over a few months.ConclusionsEven if the yellow fever vaccine is relatively safe, physicians should be aware of its possible serious adverse effects.