Journal
BIORESOURCE TECHNOLOGY
Volume 298, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.biortech.2019.122562
Keywords
Exergy analysis; Docosahexaenoic acid; Adaptive laboratory evolution; Phosphorus limitation; Schizochytrium; Fermentation
Funding
- National Natural Science Foundation of China [21576278]
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Exergy analysis is powerful tool for process optimization and mechanism analysis. In this study, exergy analysis was performed for docosahexaenoic acid (DHA) fermentation process. More than 86% of input exergy was contributed by glucose. The exergy of biomass was about 64.66% of the total output exergy when the phosphate concentration was 4 g L-1. The exergy efficiencies of DHA (eta(DHA)) for the starting strains and the evolved strains under high oxygen concentration, low temperature, and two-factor conditions were also investigated. The eta(DHA) in the collected experimental data was not more than 20.9%. It was proved that there was a positive correlation between eta DHA and the biomass yield. It was indicated that adaptive laboratory evolution (ALE) improved biomass yield which had the most important effect on enhancing eta DHA and DHA yield (or DHA productivity). It is necessary to improve eta DHA through process optimization and ALE in future.
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