Journal
BIOINFORMATICS
Volume 36, Issue 8, Pages 2618-2619Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btz938
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Funding
- Alfons und Gertrud Kassel-Stiftung
- Deutsche Forschungsgemeinschaft [HE7707/5-1]
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Motivationl: Partial differential equations (PDEs) is a well-established and powerful tool to simulate multi-cellular biological systems. However, available free tools for validation against data are on development. Results: The PDEparams module provides a flexible interface and readily accommodates different parameter analysis tools in PDE models such as computation of likelihood profiles, and parametric bootstrapping, along with direct visualization of the results. To our knowledge, it is the first open, freely available tool for parameter fitting of PDE models.
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