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Lipoic acid a multi-level molecular inhibitor of tumorigenesis

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ELSEVIER
DOI: 10.1016/j.bbcan.2019.188317

Keywords

Cancer; Lipoic acid; Apoptosis; Proliferation; Metastasis; Chemoresistance

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  1. National Council for Scientific Research of Lebanon (CNRS-L)

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We discuss how lipoic acid (LA), a natural antioxidant, induces apoptosis and inhibits proliferation, EMT, metastasis and sternness of cancer cells. Furthermore, owing to its ability to reduce chemotherapy-induced side effects and chemoresistance, LA appears to be a promising compound for cancer treatment.

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