Journal
ARCHIVES OF GERONTOLOGY AND GERIATRICS
Volume 87, Issue -, Pages -Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.archger.2019.103972
Keywords
Sex characteristics; Frail elderly; Exercise; Sedentary behavior
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Funding
- Canadian Institutes of Health Research (CIHR) Frederick Banting and Charles Best Canada Graduate Scholarship
- CIHR Strategic Training Initiative in Health Research (STIHR) Knowledge Translation Canada Student Fellowship
- CIHR STIHR Population Intervention for Chronic Disease Prevention Fellowship
- Research Manitoba Studentship
- Heart and Stroke Foundation Dr. Dexter Harvey Award
- CIHR Canada Graduate Scholarship
- CIHR Vanier Scholarship
- CIHR
- Heart and Stroke Foundation
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Objective: To investigate the sex-difference in relation to the association between moderate-vigorous physical activity (MVPA) and sedentary time (ST) patterns with frailty. Method: Accelerometry from >= 50 year olds from the National Health and Nutrition Examination Survey (2003-04/2005-06 cycles) were included. Bouted and sporadic MVPA were defined as MVPA in >= 10 min or < 10 min durations, respectively. MVPA was analyzed based on meeting 0 %, 1-49 %, 50-99 %, and >= 100 % of the physical activity guidelines of 150 min/week. A duration of >= 30 minutes defined prolonged ST. The frequency (>= 1 min interruption in ST), intensity and duration of breaks from ST were calculated. A 46-item frailty index (FI) quantified frailty. Multivariable linear regression models adjusted for demographics, total sedentary time, and accelerometer wear time. Results: There were 1143 females and 1174 males available for analysis. Bouted MVPA was associated with lower frailty levels; the association peaked at meeting 50-99 % of the guidelines in females and >= 1.0 % in males (p = NS for sex-interaction). Meeting a higher proportion of the guidelines through sporadic MVPA was significantly associated with a lower FI in males only (p = NS for sex-interaction). Prolonged ST bouts were associated with worse frailty in females but not males (p < 0.05 sex-interaction). Average break intensity was associated with a lower FI in both sexes, whereas, total sedentary breaks were not (p = NS for sex-interaction). Average break duration was associated with frailty in males (p = NS for sex-interaction). Conclusion: Prolonged ST was more detrimentally associated with frailty in females than males, which could influence tailored movement prescriptions and guidelines.
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