4.6 Article

Two-dimensional concentration of microparticles using bulk acousto-microfluidics

Journal

APPLIED PHYSICS LETTERS
Volume 116, Issue 3, Pages -

Publisher

AIP Publishing
DOI: 10.1063/1.5142670

Keywords

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Funding

  1. National Natural Science Foundation of China [11804060]
  2. Youth HundredTalents Program of Guangdong University of Technology [220413195]
  3. Seed Fund Program of the School of Electromechanical Engineering

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In this Letter, we report two-dimensional focusing of microparticles in a glass capillary whose cross section is square outside and round inside using bulk acousto-microfluidics. An imaging system allowing measurements of three-dimensional microparticle acoustophoresis is designed to simultaneously present the two-dimensional focusing processes from combinations of vertical and lateral views in a same frame. The underlying mechanisms of microparticle acoustophoresis in the glass capillary device are explained by a full-device numerical model, which solves the coupling of ultrasonic transducer, glass, and fluid layers of the experimental device. We show here that decent two-dimensional microparticle focusing can be achieved when acoustic pressure nodal lines are generated on cross sections of the fluid channel from the excitation of a single ultrasonic transducer. Based on the developed understanding, we further demonstrate here robust two-dimensional focusing of microparticles by creating an acoustic pressure node point at the channel center from excitations of two orthogonally placed ultrasonic transducers.

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