Journal
ANALYTICAL CHEMISTRY
Volume 92, Issue 7, Pages 5064-5072Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.analchem.9b05435
Keywords
-
Categories
Funding
- National Natural Science Foundation of China [81872731/21807006/91630314]
- National Science and Technology Major Projects for Major New Drugs Innovation and Development [2018ZX09711001-009-006]
Ask authors/readers for more resources
On the basis of the pyridazinone scaffold and photoinduced electron transfer (PET) mechanism, we designed a smart nitric oxide (NO) probe, PYSNO, with high sensitivity and selectivity. PYSNO exhibited a rapid response to both exogenous and endogenous NO. This probe can also be used in tracking and investigating NO generation in animal tissue. In the myocardial fibrosis model for mice, PYSNO exhibited a powerful imaging property in vivo as a result of unravelling the progressive relationship between the generation of myocardial NO and the occurrence of myocardial fibrosis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
