Journal
ADVANCED ENGINEERING MATERIALS
Volume 22, Issue 3, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adem.201901403
Keywords
electrocorticography; inkjet printing; microelectrode array; platinum; screen printing
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Funding
- Ecole Polytechnique Federale de Lausanne
- Medtronic
- Wyss Center for Bio and Neuroengineering
- Swiss National Science Foundation [200021_182670]
- Swiss National Science Foundation (SNF) [200021_182670] Funding Source: Swiss National Science Foundation (SNF)
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Bioelectronic and neuroprosthetic interfaces rely on implanted microelectrode arrays (MEAs) to interact with the human body. Printing techniques, such as inkjet and screen printing, are attractive methods for the manufacturing of MEAs because they allow flexible, room-temperature, scalable, and cost-effective fabrication processes. Herein, the fabrication of all-printed electrocorticography arrays made by inkjet printing of platinum and screen printing of polyimide is shown. Next, mechanical and electrochemical characterizations are performed. As a proof of concept, in vivo visually evoked cortical potentials are recorded in rabbits upon flash stimulation. Lastly, it is shown that the all-printed electrocorticography arrays are not cytotoxic. Altogether, the results enable the use of printed MEAs for neurological applications.
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