Journal
ACS CHEMICAL NEUROSCIENCE
Volume 11, Issue 16, Pages 2388-2390Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acschemneuro.0c00035
Keywords
Pathogens; central nervous system; genetically engineered; prions; therapeutic agents
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Pathogens are organisms that are capable of invading living bodies, often causing disease. Pathogens are inherently harmful; however, a new trend has recently emerged suggesting that pathogens could act as potential therapeutic agents. It became increasingly important to candidate pathogens for beneficial use in medicine and biological studies. Cellular barriers and immune system are powerful obstacles; however, pathogens are able to overcome these defenses, and targeting strategies, using genetically engineered pathogens, can reduce potentially damaging effects of the molecule to be delivered. The central nervous system requires more focused studies in this respect, using recently developed techniques in molecular science, such as genome manipulation.
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