4.6 Article

Multifunctional Mineral Hydrogels: Potential in Artificially Intelligent Skins and Drug Delivery

Journal

ACS OMEGA
Volume 4, Issue 21, Pages 19145-19152

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acsomega.9b02435

Keywords

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Funding

  1. National Natural Science Foundation of China [21571004]
  2. Open Project of Key Laboratory Theoretical Chemistry and Molecule Simulation of Ministry of Education, Hunan University of Science and Technology [LKF1401]
  3. Natural Science Research Project of Anhui Higher Education Institution [KJ2018A0040]

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Hydrogels have received considerable attention due to their potential applications in the fields of drug delivery, tissue engineering, and stimuli-responsive devices. Nonetheless, it is still a great difficulty in designing hydrogels with multifunctional characteristics including excellent antibacterial activity and appropriate mechanical and remarkable sensing properties. In the present study, a novel type of organic-inorganic adhesive is demonstrated, which comprises inorganic matter of amorphous calcium phosphate particles and organic substances of poly(acrylic acid) and chitosan. The hydrogel possesses excellent biocompatible and antibacterial activity, unique viscoelastic properties, high quantity of drug load, and remarkably sensitive pressure sensing, which have potential use as antibacterial biomaterials, artificially intelligent skins, and drug delivery carriers.

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