Related references
Note: Only part of the references are listed.The anti-tumor growth effect of a novel agent DMAMCL in rhabdomyosarcoma in vitro and in vivo
Ning Xu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
ROS generation and autophagosome accumulation contribute to the DMAMCL-induced inhibition of glioma cell proliferation by regulating the ROS/MAPK signaling pathway and suppressing the Akt/mTOR signaling pathway
Yanjun Wang et al.
ONCOTARGETS AND THERAPY (2019)
ACT001 can prevent and reverse tamoxifen resistance in human breast cancer cell lines by inhibiting NF-B activation
Xiao-Han Jin et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
Pharmacokinetics, tissue distribution and excretion of ACT001 in Sprague-Dawley rats and metabolism of ACT001
Xiao-Nan Xi et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2019)
Application of sesquiterpene lactone: A new promising way for cancer therapy based on anticancer activity
Ghader Babaei et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia
Jing Li et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
The Metabolic Chemical Reporter 6-Azido-6-deoxy-glucose Further Reveals the Substrate Promiscuity of O-GlcNAc Transferase and Catalyzes the Discovery of Intracellular Protein Modification by O-Glucose
Narek Darabedian et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)
Pyruvate kinase M2 fuels multiple aspects of cancer cells: from cellular metabolism, transcriptional regulation to extracellular signaling
Ming-Chuan Hsu et al.
MOLECULAR CANCER (2018)
Inhibition of Radiation and Temozolomide-Induced Invadopodia Activity in Glioma Cells Using FDA-Approved Drugs
Clarissa A. Whitehead et al.
TRANSLATIONAL ONCOLOGY (2018)
Metabolic Profiles in cell Lines Infeted with Classical Swine Fever Virus
Hongchao Gou et al.
FRONTIERS IN MICROBIOLOGY (2017)
Antineoplastic effects and mechanisms of micheliolide in acute myelogenous leukemia stem cells
Qing Ji et al.
ONCOTARGET (2016)
Role of isoenzyme M2 of pyruvate kinase in urothelial tumorigenesis
Haiping Zhou et al.
ONCOTARGET (2016)
Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain
Ting Dong et al.
SCIENTIFIC REPORTS (2016)
Pyruvate Kinase Isoform Expression Alters Nucleotide Synthesis to Impact Cell Proliferation
Sophia Y. Lunt et al.
MOLECULAR CELL (2015)
Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine
Ting Dong et al.
NATURE COMMUNICATIONS (2015)
The Warburg effect: molecular aspects and therapeutic possibilities
Hanh Ngo et al.
MOLECULAR BIOLOGY REPORTS (2015)
Micheliolide Derivative DMAMCL Inhibits Glioma Cell Growth In Vitro and In Vivo
Yinghong An et al.
PLOS ONE (2015)
Epidemiologic and Molecular Prognostic Review of Glioblastoma
Jigisha P. Thakkar et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2014)
Antiangiogenic Therapy for Glioblastoma: Current Status and Future Prospects
Tracy T. Batchelor et al.
CLINICAL CANCER RESEARCH (2014)
Tumor aerobic glycolysis: new insights into therapeutic strategies with targeted delivery
Meghna Talekar et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2014)
Activators of PKM2 in cancer metabolism
Steven L. Warner et al.
FUTURE MEDICINAL CHEMISTRY (2014)
Targeting adaptive glioblastoma: an overview of proliferation and invasion
Qian Xie et al.
NEURO-ONCOLOGY (2014)
Parthenolide: from plant shoots to cancer roots
Akram Ghantous et al.
DRUG DISCOVERY TODAY (2013)
Glioblastoma and Other Malignant Gliomas A Clinical Review
Antonio Omuro et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2013)
Pyruvate Kinase M2 Expression, but Not Pyruvate Kinase Activity, Is Up-Regulated in a Grade-Specific Manner in Human Glioma
Joydeep Mukherjee et al.
PLOS ONE (2013)
The Metabolomic Signature of Malignant Glioma Reflects Accelerated Anabolic Metabolism
Prakash Chinnaiyan et al.
CANCER RESEARCH (2012)
Small Molecule Activation of PKM2 in Cancer Cells Induces Serine Auxotrophy
Charles Kung et al.
CHEMISTRY & BIOLOGY (2012)
Pyruvate Kinase M2: Multiple Faces for Conferring Benefits on Cancer Cells
Mayumi Tamada et al.
CLINICAL CANCER RESEARCH (2012)
Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression
Michael S. Goldberg et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Guaianolide Sesquiterpene Lactones, a Source To Discover Agents That Selectively Inhibit Acute Myelogenous Leukemia Stern and Progenitor Cells
Quan Zhang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Biomimetic Semisynthesis of Arglabin from Parthenolide
Jia-Dai Zhai et al.
JOURNAL OF ORGANIC CHEMISTRY (2012)
Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
Dimitrios Anastasiou et al.
NATURE CHEMICAL BIOLOGY (2012)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
Qian Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Otto Warburg's contributions to current concepts of cancer metabolism
Willem H. Koppenol et al.
NATURE REVIEWS CANCER (2011)
Regulation of cancer cell metabolism
Rob A. Cairns et al.
NATURE REVIEWS CANCER (2011)
Identification of small molecule inhibitors of pyruvate kinase M2
Matthew G. Vander Heiden et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells
Benjamin Kefas et al.
NEURO-ONCOLOGY (2010)
Brain Tumor Stem Cells as Therapeutic Targets in Models of Glioma
Dan Richard Laks et al.
YONSEI MEDICAL JOURNAL (2010)
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
Roger Stupp et al.
LANCET ONCOLOGY (2009)
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Heather R. Christofk et al.
NATURE (2008)
Epidemiology and molecular pathology of glioma
Judith A. Schwartzbaum et al.
NATURE CLINICAL PRACTICE NEUROLOGY (2006)
Share Paper
