4.6 Article

The Oncogenic Signaling Pathways in BRAF-Mutant Melanoma Cells Are Modulated by Naphthalene Diimide-Like G-Quadruplex Ligands

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Naphthalene Diimides as Multimodal G-Quadruplex-Selective Ligands

Valentina Pirota et al.

MOLECULES (2019)

Review Biochemistry & Molecular Biology

Many ways to resistance: How melanoma cells evade targeted therapies

Ines Kozar et al.

BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2019)

Review Chemistry, Organic

Binding and Beyond: What Else Can G-Quadruplex Ligands Do?

Michael P. O'Hagan et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

c-MYC G-quadruplex binding by the RNA polymerase I inhibitor BMH-21 and analogues revealed by a combined NMR and biochemical Approach

Loana Musso et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2018)

Review Chemistry, Medicinal

Dual or multi-targeting inhibitors: The next generation anticancer agents

Nulgumnalli Manjunathaiah Raghavendra et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

More is not always better: finding the right trade-off between affinity and selectivity of a G-quadruplex ligand

Michela Zuffo et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Multidisciplinary Sciences

Transcriptome-wide identification of transient RNA G-quadruplexes in human cells

Sunny Y. Yang et al.

NATURE COMMUNICATIONS (2018)

Article Medicine, Research & Experimental

G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

Roberto Simone et al.

EMBO MOLECULAR MEDICINE (2018)

Article Multidisciplinary Sciences

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Hong Xu et al.

NATURE COMMUNICATIONS (2017)

Article Multidisciplinary Sciences

The cellular protein hnRNP A2/B1 enhances HIV-1 transcription by unfolding LTR promoter G-quadruplexes

Matteo Scalabrin et al.

SCIENTIFIC REPORTS (2017)

Review Chemistry, Multidisciplinary

Quadruplex nucleic acids as targets for anticancer therapeutics

Stephen Neidle

NATURE REVIEWS CHEMISTRY (2017)

Review Oncology

Novel Targeted Therapies for Metastatic Melanoma

Wade T. Iams et al.

CANCER JOURNAL (2017)

Article Genetics & Heredity

G-quadruplex structures mark human regulatory chromatin

Robert Hansel-Hertsch et al.

NATURE GENETICS (2016)

Article Biochemistry & Molecular Biology

G-quadruplexes and helicases

Oscar Mendoza et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Pharmacology & Pharmacy

Emerging Role of G-quadruplex DNA as Target in Anticancer Therapy

Graziella Cimino-Reale et al.

CURRENT PHARMACEUTICAL DESIGN (2016)

Article Pharmacology & Pharmacy

The Genetic Basis of New Treatment Modalities in Melanoma

Manfred Kunz

CURRENT DRUG TARGETS (2015)

Review Dermatology

Alternative Treatments For Melanoma: Targeting BCL-2 Family Members to De-Bulk and Kill Cancer Stem Cells

Nabanita Mukherjee et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)

Article Chemistry, Multidisciplinary

Stability and Kinetics of c-MYC Promoter G-Quadruplexes Studied by Single-Molecule Manipulation

Huijuan You et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)

Article Biochemistry & Molecular Biology

The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures

Jia Zhou et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Biochemistry & Molecular Biology

G-quadruplexes and their regulatory roles in biology

Daniela Rhodes et al.

NUCLEIC ACIDS RESEARCH (2015)

Article Chemistry, Multidisciplinary

The Major G-Quadruplex Formed in the Human BCL-2 Proximal Promoter Adopts a Parallel Structure with a 13-nt Loop in K+ Solution

Prashansa Agrawal et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Biochemistry & Molecular Biology

Detection of G-quadruplex DNA in mammalian cells

Alexander Henderson et al.

NUCLEIC ACIDS RESEARCH (2014)

Article Biochemistry & Molecular Biology

Regulation of Telomere Length by G-Quadruplex Telomere DNA- and TERRA-Binding Protein TLS/FUS

Kentaro Takahama et al.

CHEMISTRY & BIOLOGY (2013)

Editorial Material Oncology

Targeting Activated KIT Signaling for Melanoma Therapy

Boris C. Bastian et al.

JOURNAL OF CLINICAL ONCOLOGY (2013)

Article Chemistry, Medicinal

A Dynamic G-Quadruplex Region Regulates the HIV-1 Long Terminal Repeat Promoter

Rosalba Perrone et al.

JOURNAL OF MEDICINAL CHEMISTRY (2013)

Article Chemistry, Multidisciplinary

Crystal Structure of a Promoter Sequence in the B-raf Gene Reveals an Intertwined Dimer Quadruplex

Dengguo Wei et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Multidisciplinary Sciences

Pif1 family helicases suppress genome instability at G-quadruplex motifs

Katrin Paeschke et al.

NATURE (2013)

Article Chemistry, Multidisciplinary

Quantitative visualization of DNA G-quadruplex structures in human cells

Giulia Biffi et al.

NATURE CHEMISTRY (2013)

Review Biotechnology & Applied Microbiology

Vemurafenib: the first drug approved for BRAF-mutant cancer

Gideon Bollag et al.

NATURE REVIEWS DRUG DISCOVERY (2012)

Article Chemistry, Organic

Hybrid ligand-alkylating agents targeting telomeric G-quadruplex structures

Filippo Doria et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2012)

Article Biotechnology & Applied Microbiology

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

Shankar Balasubramanian et al.

NATURE REVIEWS DRUG DISCOVERY (2011)

Review Biochemistry & Molecular Biology

Making sense of G-quadruplex and i-motif functions in oncogene promoters

Tracy A. Brooks et al.

FEBS JOURNAL (2010)

Review Biochemistry & Molecular Biology

Structure, location and interactions of G-quadruplexes

Julian L. Huppert

FEBS JOURNAL (2010)

Review Biochemistry & Molecular Biology

The structures of quadruplex nucleic acids and their drug complexes

Stephen Neidle

CURRENT OPINION IN STRUCTURAL BIOLOGY (2009)

Review Biochemistry & Molecular Biology

Expression and Function of Bcl-2 Proteins in Melanoma

Juergen Eberle et al.

CURRENT GENOMICS (2008)

Review Chemistry, Organic

A hitchhiker's guide to G-quadruplex ligands

David Monchaud et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2008)

Article Biochemical Research Methods

Quadruplex melting

Phillip A. Rachwal et al.

METHODS (2007)

Article Biochemistry & Molecular Biology

G-quadruplexes in promoters throughout the human genome

Julian L. Huppert et al.

NUCLEIC ACIDS RESEARCH (2007)

Review Biochemistry & Molecular Biology

Quadruplex DNA: sequence, topology and structure

Sarah Burge et al.

NUCLEIC ACIDS RESEARCH (2006)

Article Biochemistry & Molecular Biology

A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene

Himesh Fernando et al.

BIOCHEMISTRY (2006)

Article Chemistry, Multidisciplinary

Putative DNA quadruplex formation within the human c-kit oncogene

S Rankin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Multidisciplinary Sciences

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

A Siddiqui-Jain et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)