Related references
Note: Only part of the references are listed.Preferential Response of Basal-Like Head and Neck Squamous Cell Carcinoma Cell Lines to EGFR-Targeted Therapy Depending on EREG-Driven Oncogenic Addiction
Sylvie Job et al.
CANCERS (2019)
HIF-2α promotes conversion to a stem cell phenotype and induces chemoresistance in breast cancer cells by activating Wnt and Notch pathways
Yuanyuan Yan et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Sorafenib resistance in hepatocarcinoma: role of hypoxia-inducible factors
Carolina Mendez-Blanco et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2018)
Targeting Tumor Adaption to Chronic Hypoxia: Implications for Drug Resistance, and How It Can Be Overcome
Jae-Young Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Drug Resistance Driven by Cancer Stem Cells and Their Niche
Marta Prieto-Vila et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Differential pattern of HIF-1α expression in HNSCC cancer stem cells after carbon ion or photon irradiation: one molecular explanation of the oxygen effect
Anne -Sophie Wozny et al.
BRITISH JOURNAL OF CANCER (2017)
Prognostic and predictive value of EGFR in head and neck squamous cell carcinoma
Paolo Bossi et al.
ONCOTARGET (2016)
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217-and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
Chuanzhao Zhang et al.
ONCOTARGET (2016)
Endothelial PAS domain-containing protein 1 confers TKI-resistance by mediating EGFR and MET pathways in non-small cell lung cancer cells
Qiang Zhen et al.
CANCER BIOLOGY & THERAPY (2015)
Intermittent Hypoxia Selects for Genotypes and Phenotypes That Increase Survival, Invasion, and Therapy Resistance
Daniel Verduzco et al.
PLOS ONE (2015)
Upregulation of HIF-2α induced by sorafenib contributes to the resistance by activating the TGF-α/EGFR pathway in hepatocellular carcinoma cells
Dali Zhao et al.
CELLULAR SIGNALLING (2014)
Carbon ion radiotherapy of human lung cancer attenuates HIF-1 signaling and acts with considerably enhanced therapeutic efficiency
Florentine S. B. Subtil et al.
FASEB JOURNAL (2014)
mTOR Co-Targeting in Cetuximab Resistance in Head and Neck Cancers Harboring PIK3CA and RAS Mutations
Zhiyong Wang et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2014)
A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer
Helmout Modjtahedi et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2014)
HIF-2α Regulates NANOG Expression in Human Embryonic Stem Cells following Hypoxia and Reoxygenation through the Interaction with an Oct-Sox Cis Regulatory Element
Raffaella Petruzzelli et al.
PLOS ONE (2014)
Melittin enhances radiosensitivity of hypoxic head and neck squamous cell carcinoma by suppressing HIF-1α
Xi Yang et al.
TUMOR BIOLOGY (2014)
Anti-Epidermal Growth Factor Receptor Therapy in Head and Neck Squamous Cell Carcinoma: Focus on Potential Molecular Mechanisms of Drug Resistance
Carolien Boeckx et al.
ONCOLOGIST (2013)
Preclinical modeling of EGFR inhibitor resistance in head and neck cancer
Kelly M. Quesnelle et al.
CANCER BIOLOGY & THERAPY (2012)
The anti-EGFR antibody cetuximab sensitizes human head and neck squamous cell carcinoma cells to radiation in part through inhibiting radiation-induced upregulation of HIF-1α
Haiquan Lu et al.
CANCER LETTERS (2012)
Passing the baton: the HIF switch
Mei Yee Koh et al.
TRENDS IN BIOCHEMICAL SCIENCES (2012)
Targeting TORC1/2 Enhances Sensitivity to EGFR Inhibitors in Head and Neck Cancer Preclinical Models
Andre Cassell et al.
NEOPLASIA (2012)
The Hypoxia-Associated Factor Switches Cells from HIF-1α- to HIF-2α-Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion
Mei Yee Koh et al.
CANCER RESEARCH (2011)
Stabilisation and Knockdown of HIF - Two Distinct Ways Comparably Important in Radiotherapy
Mareike Stroefer et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2011)
New Strategies in Head and Neck Cancer: Understanding Resistance to Epidermal Growth Factor Receptor Inhibitors
Lucy F. Chen et al.
CLINICAL CANCER RESEARCH (2010)
Comparison of radiosensitizing effects of the mammalian target of rapamycin inhibitor CCI-779 to cisplatin in experimental models of head and neck squamous cell carcinoma
Oleksandr Ekshyyan et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Generating specificity and diversity in the transcriptional response to hypoxia
Urban Lendahl et al.
NATURE REVIEWS GENETICS (2009)
Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction
Bikul Das et al.
STEM CELLS (2008)
HYPOXIA AND METABOLISM SERIES - TIMELINE The impact of O2 availability on human cancer
Jessica A. Bertout et al.
NATURE REVIEWS CANCER (2008)
Review: Implications of in vitro research on the effect of radiotherapy and chemotherapy under hypoxic conditions
An Wouters et al.
ONCOLOGIST (2007)
The relation between hypoxia-inducible factor (HIF)-1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer
Stuart C. Winter et al.
CANCER (2006)
Effects of smoking on the pharmacokinetics of erlotinib
M Hamilton et al.
CLINICAL CANCER RESEARCH (2006)
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck
JA Bonner et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1α
RJ Phillips et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer
MI Koukourakis et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2002)