Related references
Note: Only part of the references are listed.Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma
Chun Jye Lim et al.
GUT (2019)
Characteristics of Immune Response to Tumor-Associated Antigens and Immune Cell Profile in Patients With Hepatocellular Carcinoma
Yuki Inada et al.
HEPATOLOGY (2019)
Nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh class B cirrhosis: Safety and clinical outcomes in a retrospective case series
Swetha Kambhampati et al.
CANCER (2019)
Comparison of immune infiltrates in melanoma and pancreatic cancer highlights VISTA as a potential target in pancreatic cancer
Jorge Blando et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
TGF-β as Multifaceted Orchestrator in HCC Progression: Signaling, EMT, Immune Microenvironment, and Novel Therapeutic Perspectives
Francesco Dituri et al.
SEMINARS IN LIVER DISEASE (2019)
Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients
V. Gopalakrishnan et al.
SCIENCE (2018)
VISTA expression associated with CD8 confers a favorable immune microenvironment and better overall survival in hepatocellular carcinoma
Ming Zhang et al.
BMC CANCER (2018)
VISTA expression on tumor-infiltrating inflammatory cells in primary cutaneous melanoma correlates with poor disease-specific survival
Lawrence F. Kuklinski et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2018)
MAIT cells are chronically activated in patients with autoimmune liver disease and promote profibrogenic hepatic stellate cell activation
Katrin Bottcher et al.
HEPATOLOGY (2018)
Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial
Andrew X. Zhu et al.
LANCET ONCOLOGY (2018)
Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research
Zachary J. Brown et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2018)
Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells
Chi Ma et al.
SCIENCE (2018)
Hyper-Expression of PD-1 Is Associated with the Levels of Exhausted and Dysfunctional Phenotypes of Circulating CD161++TCR iVα7.2+ Mucosal-Associated Invariant T Cells in Chronic Hepatitis B Virus Infection
Yean K. Yong et al.
FRONTIERS IN IMMUNOLOGY (2018)
Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
P. Schmid et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Carcinogenesis on the background of liver fibrosis: Implications for the management of hepatocellular cancer
Joanne Marie O'Rourke et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2018)
Personalized identification of tumor-associated immunogenic neoepitopes in hepatocellular carcinoma in complete remission after sorafenib treatment
Sindy Vrecko et al.
Oncotarget (2018)
A novel spontaneous hepatocellular carcinoma mouse model for studying T-cell exhaustion in the tumor microenvironment
Yu-Tzu Liu et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
Current frontline approaches in the management of hepatocellular carcinoma: the evolving role of immunotherapy
Gagandeep Brar et al.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2018)
Immunotherapy of Hepatocellular Carcinoma: Facts and Hopes
Mercedes Inarrairaegui et al.
CLINICAL CANCER RESEARCH (2018)
CD4 +Foxp3+ T Cells Promote Aberrant Immunoglobulin G Production and Maintain CD8+ T-Cell Suppression During Chronic Liver Disease
Dana Tedesco et al.
HEPATOLOGY (2017)
Antibodies Against Immune Checkpoint Molecules Restore Functions of Tumor-Infiltrating T Cells in Hepatocellular Carcinomas
Guoying Zhou et al.
GASTROENTEROLOGY (2017)
Incidence of Hepatocellular Carcinoma in All 50 United States, From 2000 Through 2012
Donna L. White et al.
GASTROENTEROLOGY (2017)
Transplant trials with Tregs: perils and promises
Qizhi Tang et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model
Guangfu Li et al.
JOURNAL OF HEPATOLOGY (2017)
Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma
Austin G. Duffy et al.
JOURNAL OF HEPATOLOGY (2017)
Levels of hepatic Th17 cells and regulatory T cells upregulated by hepatic stellate cells in advanced HBV-related liver fibrosis
Xiaoyan Li et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2017)
Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial
Anthony B. El-Khoueiry et al.
LANCET (2017)
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
Shabnam Shalapour et al.
NATURE (2017)
Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma
J. Bellmunt et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Tumor Mutational Burden and Response Rate to PD-1 Inhibition
Mark Yarchoan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Tumor regulation of the tissue environment in the liver
Tobias Eggert et al.
PHARMACOLOGY & THERAPEUTICS (2017)
Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses
Valerie Chew et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Th17/Treg imbalance is an indicator of liver cirrhosis process and a risk factor for HCC occurrence in HBV patients
Kun Li et al.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY (2017)
Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC
Paul C. Tumeh et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Safety in treatment of hepatocellular carcinoma with immune checkpoint inhibitors as compared to melanoma and non-small cell lung cancer
Zachary J. Brown et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2017)
Characterization of the Immune Microenvironment in Hepatocellular Carcinoma
Mark Yarchoan et al.
CLINICAL CANCER RESEARCH (2017)
Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing
Chunhong Zheng et al.
CELL (2017)
PD-1 and PD-L1 antibodies in cancer: current status and future directions
Arjun Vasant Balar et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2017)
Liver macrophages in tissue homeostasis and disease
Oliver Krenkel et al.
NATURE REVIEWS IMMUNOLOGY (2017)
NKT cell subsets as key participants in liver physiology and pathology
Keya Bandyopadhyay et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2016)
Spontaneous and induced tolerance for liver transplant recipients
Sandy Feng
CURRENT OPINION IN ORGAN TRANSPLANTATION (2016)
TGF-β signalling and liver disease
Isabel Fabregat et al.
FEBS JOURNAL (2016)
Immunology in the liver - from homeostasis to disease
Felix Heymann et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2016)
PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma
Paul T. Nghiem et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
R. L. Ferris et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Clinical relevance of circulating mucosal-associated invariant T cell levels and their anti-cancer activity in patients with mucosal-associated cancer
Eun Jeong Won et al.
ONCOTARGET (2016)
Tim-3 fosters HCC development by enhancing TGF-β-mediated alternative activation of macrophages
Wenjiang Yan et al.
GUT (2015)
Liver inflammation abrogates immunological tolerance induced by Kupffer cells
Felix Heymann et al.
HEPATOLOGY (2015)
CXCR4 Inhibition in Tumor Microenvironment Facilitates Anti-Programmed Death Receptor-1 Immunotherapy in Sorafenib-Treated Hepatocellular Carcinoma in Mice
Yunching Chen et al.
HEPATOLOGY (2015)
Immune Checkpoint Blockade in Cancer Therapy
Michael A. Postow et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses
Norman Woller et al.
MOLECULAR THERAPY (2015)
Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs
Mahzad Akbarpour et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Prognosis of Untreated Hepatocellular Carcinoma
Edoardo G. Giannini et al.
HEPATOLOGY (2015)
Immunodominance and Functional Alterations of Tumor-Associated Antigen-Specific CD8+ T-Cell Responses in Hepatocellular Carcinoma
Tobias Flecken et al.
HEPATOLOGY (2014)
Transforming Growth Factor-β Signaling in Hepatocytes Promotes Hepatic Fibrosis and Carcinogenesis in Mice With Hepatocyte-Specific Deletion of TAK1
Ling Yang et al.
GASTROENTEROLOGY (2013)
Natural killer cells in liver disease
Zhigang Tian et al.
HEPATOLOGY (2013)
Virus-induced hepatocellular carcinomas cause antigen-specific local tolerance
Gerald Willimsky et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis
Yoon Seok Roh et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2013)
A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
Bruno Sangro et al.
JOURNAL OF HEPATOLOGY (2013)
Early IL-17 Production by Intrahepatic T Cells Is Important for Adaptive Immune Responses in Viral Hepatitis
Lifei Hou et al.
JOURNAL OF IMMUNOLOGY (2013)
Chemokine Receptor CXCR6-Dependent Hepatic NK T Cell Accumulation Promotes Inflammation and Liver Fibrosis
Alexander Wehr et al.
JOURNAL OF IMMUNOLOGY (2013)
A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection
David Gardiner et al.
PLOS ONE (2013)
Soluble CD163, a marker of Kupffer cell activation, is related to portal hypertension in patients with liver cirrhosis
H. Gronbaek et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2012)
Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO
Tuanjie Li et al.
CANCER LETTERS (2012)
Interleukin-17 Signaling in Inflammatory, Kupffer Cells, and Hepatic Stellate Cells Exacerbates Liver Fibrosis in Mice
Fanli Meng et al.
GASTROENTEROLOGY (2012)
Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma
Valerie Chew et al.
GUT (2012)
NKp46-mediated killing of human and mouse hepatic stellate cells attenuates liver fibrosis
Chamutal Gur et al.
GUT (2012)
Natural killer p46High expression defines a natural killer cell subset that is potentially involved in control of hepatitis C virus replication and modulation of liver fibrosis
Benjamin Kraemer et al.
HEPATOLOGY (2012)
Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer
Suzanne L. Topalian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells
Mathilde Dusseaux et al.
BLOOD (2011)
Suppression of Innate Immunity (Natural Killer Cell/Interferon-γ) in the Advanced Stages of Liver Fibrosis in Mice
Won-Il Jeong et al.
HEPATOLOGY (2011)
Comparative Analysis of Various Tumor-Associated Antigen-Specific T-Cell Responses in Patients with Hepatocellular Carcinoma
Eishiro Mizukoshi et al.
HEPATOLOGY (2011)
Nuclear Factor High-Mobility Group Box1 Mediating the Activation of Toll-Like Receptor 4 Signaling in Hepatocytes in the Early Stage of Nonalcoholic Fatty Liver Disease in Mice
Liang Li et al.
HEPATOLOGY (2011)
Role of toll-like receptor impairment in cirrhosis infection risk: are we making progress?
Pedro Pimentel-Nunes et al.
LIVER INTERNATIONAL (2011)
CURRENT CONCEPTS Hepatocellular Carcinoma
Hashem B. El-Serag
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Selective Recruitment of Regulatory T Cell through CCR6-CCL20 in Hepatocellular Carcinoma Fosters Tumor Progression and Predicts Poor Prognosis
Kang-Jie Chen et al.
PLOS ONE (2011)
Chronic Alcohol Consumption Is Associated With an Increased Cytotoxic Profile of Circulating Lymphocytes That May Be Related With the Development of Liver Injury
Francisco Javier Laso et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2010)
Mannose-binding lectin deficiency confers risk for bacterial infections in a large Hungarian cohort of patients with liver cirrhosis
Istvan Altorjay et al.
JOURNAL OF HEPATOLOGY (2010)
Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients
Valerie Chew et al.
JOURNAL OF HEPATOLOGY (2010)
Functional Contribution of Elevated Circulating and Hepatic Non-Classical CD14+CD16+ Monocytes to Inflammation and Human Liver Fibrosis
Henning W. Zimmermann et al.
PLOS ONE (2010)
Antigen-presenting cell function in the tolerogenic liver environment
Angus W. Thomson et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Role of Toll-like receptors 2, 4, and 9 in mediating neutrophil dysfunction in alcoholic hepatitis
V. Stadlbauer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Kupffer Cell Suppression of CD8+ T Cells in Human Hepatocellular Carcinoma Is Mediated by B7-H1/Programmed Death-1 Interactions
Ke Wu et al.
CANCER RESEARCH (2009)
Liver tumor infiltrating lymphocytes: Comparison of hepatocellular and cholangiolar carcinoma
Hans-Udo Kasper et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2009)
Analysis of monocyte chemotactic protein-1 gene polymorphism in patients with spontaneous bacterial peritonitis
Erwin Gaebele et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2009)
New insights into mechanisms of spontaneous liver transplant tolerance:: The role of Foxp3-expressing CD25+CD4+ regulatory T cells
W. Li et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2008)
Functional impairment in circulating and intrahepatic NK cells and relative mechanism in hepatocellular carcinoma patients
Lun Cai et al.
CLINICAL IMMUNOLOGY (2008)
A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4+CD25+Foxp3+ T cells
Bastian Hoechst et al.
GASTROENTEROLOGY (2008)
Abrogation of the antifibrotic effects of natural killer cells/interferon-gamma contributes to alcohol acceleration of liver fibrosis
Won-Il Jeong et al.
GASTROENTEROLOGY (2008)
Molecular mechanism of hepatic stellate cell activation and antifibrotic therapeutic strategies
Jing-Ting Li et al.
JOURNAL OF GASTROENTEROLOGY (2008)
Sorafenib in advanced hepatocellular carcinoma
Josep M. Llovet et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Bacterial infections, sepsis, and multiorgan failure in cirrhosis
Puneeta Tandon et al.
SEMINARS IN LIVER DISEASE (2008)
Liver: An organ with predominant innate immunity
Bin Gao et al.
HEPATOLOGY (2008)
Endotoxemia contributes to the immune paralysis in patients with cirrhosis
Chun-Yen Lin et al.
JOURNAL OF HEPATOLOGY (2007)
Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection
Carolina Boni et al.
JOURNAL OF VIROLOGY (2007)
Role of Kupffer cells in host defense and liver disease
Manfred Bilzer et al.
LIVER INTERNATIONAL (2006)
STAT1 inhibits liver fibrosis in mice by inhibiting stellate cell proliferation and stimulating NK cell cytotoxicity
Won-Il Jeong et al.
HEPATOLOGY (2006)
Tumour lymphocytic infiltrate and recurrence of hepatocellular carcinoma following liver transplantation
Esther Unitt et al.
JOURNAL OF HEPATOLOGY (2006)
Pattern recognition receptors: A contemporary view on liver diseases
Gyongyi Szabo et al.
HEPATOLOGY (2006)
Tumour necrosis factor α signalling through activation of Kupffer cells plays an essential role in liver fibrosis of non-alcoholic steatohepatitis in mice
K Tomita et al.
GUT (2006)
The liver as an immunological organ
V Racanelli et al.
HEPATOLOGY (2006)
Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas
M Jinushi et al.
JOURNAL OF HEPATOLOGY (2005)
Compromised lymphocytes infiltrate hepatocellular carcinoma: The role of T-regulatory cells
E Unitt et al.
HEPATOLOGY (2005)
Bacterial translocation (BT) in cirrhosis
R Wiest et al.
HEPATOLOGY (2005)
Fibrosis in chronic liver diseases: diagnosis and management
M Pinzani et al.
JOURNAL OF HEPATOLOGY (2005)
Tumour necrosis factor-alpha expression by activated monocytes and altered T-cell homeostasis in ascitic alcoholic cirrhosis:: amelioration with norfloxacin
A Albillos et al.
JOURNAL OF HEPATOLOGY (2004)
Distinct subpopulations of γδ T cells are present in normal and tumor-bearing human liver
T Kenna et al.
CLINICAL IMMUNOLOGY (2004)
Going both ways: immune regulation via CD1d-dependent NKT cells
DI Godfrey et al.
JOURNAL OF CLINICAL INVESTIGATION (2004)
Hepatocellular carcinoma in cirrhosis: Incidence and risk factors
G Fattovich et al.
GASTROENTEROLOGY (2004)
NKT and CD8 lymphocytes mediate suppression of hepatocellular carcinoma growth via tumor antigen-pulsed dendritic cells
O Shibolet et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
PD-1 inhibits antiviral immunity at the effector phase in the liver
YH Iwai et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Induction of immune tolerance to coagulation factor IX antigen by in vivo hepatic gene transfer
F Mingozzi et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
Expression of inhibitory receptors in, natural killer (CD3-CD56+) cells and CD3+CD56+ cells in the peripheral blood lymphocytes and tumor infiltrating lymphocytes in patients with primary hepatocellular carcinoma
MF Yuen et al.
CLINICAL IMMUNOLOGY (2001)
Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance
A Limmer et al.
NATURE MEDICINE (2000)