4.4 Article

Folic-Acid-Functionalized Magnetic Nanoparticles as Green and Magnetic Recyclable Catalyst for the Synthesis of 4-Aryl-NH-1,2,3-triazoles in a Green Media

Journal

CHEMISTRYSELECT
Volume 4, Issue 40, Pages 11930-11935

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/slct.201902205

Keywords

Choline azide; Folic acid; Magnetic catalyst; Organocatalyst; Triazoles

Funding

  1. Faculty of the chemistry of Tarbiat Modares University

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A useful, robust, and cheap procedure was obtained for the synthesis of 4-aryl-NH-1,2,3-triazoles via aromatic aldehydes, nitromethane and choline azide in the presence of folic acid immobilized magnetic nanoparticle with good yields. The magnetic catalyst is easily synthesized and can be recycled at least five times with no significant loss in activity. In addition, the choline azide is used as a reagent and green solvent.

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