Related references
Note: Only part of the references are listed.Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors
Yang Yang et al.
CELL DEATH & DISEASE (2019)
THE FIRST PHASE 2A PROOF-OF-CONCEPT STUDY OF A SELECTIVE NLRP3 INFLAMMASOME INHIBITOR, DAPANSUTRILE™ (OLT1177™), IN ACUTE GOUT
T. L. Jansen et al.
ANNALS OF THE RHEUMATIC DISEASES (2019)
OLT1177™, AN ORAL NLRP3 INFLAMMASOME INHIBITOR, INHIBITS ACUTE JOINT INFLAMMATION AND CIRCULATING IL 1β DURING GOUT FLARES IN HUMANS
V. Kluck et al.
ANNALS OF THE RHEUMATIC DISEASES (2019)
Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain
Nemat Khan et al.
INFLAMMOPHARMACOLOGY (2018)
IL-1β enables CNS access to CCR2hi monocytes and the generation of pathogenic cells through GM-CSF released by CNS endothelial cells
Alexandre Pare et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
OLT1177, a ß-sulfonyl nitrile compound, safe in humans, inhibits the NLRP3 inflammasome and reverses the metabolic cost of inflammation
Carlo Marchetti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Targeting NLRP3 Inflammasome in the Treatment of CNS Diseases
Bo-Zong Shao et al.
FRONTIERS IN MOLECULAR NEUROSCIENCE (2018)
NLRP3 inflammasome inhibitor OLT1177 suppresses joint inflammation in murine models of acute arthritis
Carlo Marchetti et al.
ARTHRITIS RESEARCH & THERAPY (2018)
Cytokine networks in neuroinflammation
Burkhard Becher et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Further understanding of the immunopathology of multiple sclerosis: impact on future treatments
Vikram Bhise et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2016)
Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice
Sebastien A. Levesque et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
A basic overview of multiple sclerosis immunopathology
N. Grigoriadis et al.
EUROPEAN JOURNAL OF NEUROLOGY (2015)
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Rebecca C. Coll et al.
NATURE MEDICINE (2015)
Immunopathology of multiple sclerosis
Calliope A. Dendrou et al.
NATURE REVIEWS IMMUNOLOGY (2015)
The analysis of correlation between IL-1B gene expression and genotyping in multiple sclerosis patients
Masoumeh Heidary et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2014)
Interleukin-1β causes excitotoxic neurodegeneration and multiple sclerosis disease progression by activating the apoptotic protein p53
Silvia Rossi et al.
MOLECULAR NEURODEGENERATION (2014)
Inflammasomes in health and disease
Till Strowig et al.
NATURE (2012)
Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases
Charles A. Dinarello et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond
Cristina Conforti-Andreoni et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2011)
The NLRP3 inflammasome in health and disease: the good, the bad and the ugly
P. Menu et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2011)
The Immunopathophysiology of Multiple Sclerosis
Gregory F. Wu et al.
NEUROLOGIC CLINICS (2011)
NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses
Denis Gris et al.
JOURNAL OF IMMUNOLOGY (2010)
Critical Regulation of Early Th17 Cell Differentiation by Interleukin-1 Signaling
Yeonseok Chung et al.
IMMUNITY (2009)
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
Luigi Franchi et al.
NATURE IMMUNOLOGY (2009)
The immunopathology of multiple sclerosis:: An overview
Hans Lassmann et al.
BRAIN PATHOLOGY (2007)
CATERPILLERs, pyrin and hereditary immunological disorders
JPY Ting et al.
NATURE REVIEWS IMMUNOLOGY (2006)
The inflammasome:: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
F Martinon et al.
MOLECULAR CELL (2002)
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
J Feldmann et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2002)
Caspase-1 expression in multiple sclerosis plaques and cultured glial cells
X Ming et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2002)
Production of IL-1β and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis
BA de Jong et al.
JOURNAL OF NEUROIMMUNOLOGY (2002)
IL-18 in patients with multiple sclerosis
J Losy et al.
ACTA NEUROLOGICA SCANDINAVICA (2001)
Increased serum levels of interleukin-18 in patients with multiple sclerosis
F Nicoletti et al.
NEUROLOGY (2001)
IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-γ by NK cells
FD Shi et al.
JOURNAL OF IMMUNOLOGY (2000)
Share Paper
