4.7 Article

iW-Net: an automatic and minimalistic interactive lung nodule segmentation deep network

Journal

SCIENTIFIC REPORTS
Volume 9, Issue -, Pages -

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41598-019-48004-8

Keywords

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Funding

  1. FCT [SFRH/BD/120435/2016, SFRH/BD/122365/2016]
  2. ERDF - European Regional Development Fund through Operational Programme for Competitiveness - COMPETE 2020 Programme [NLST-375]
  3. National Fundus through the Portuguese funding agency, FCT - Fundacao para a Ciencia e Tecnologia [POCI-01-0145-FEDER-016673]

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We propose iW-Net, a deep learning model that allows for both automatic and interactive segmentation of lung nodules in computed tomography images. iW-Net is composed of two blocks: the first one provides an automatic segmentation and the second one allows to correct it by analyzing 2 points introduced by the user in the nodule's boundary. For this purpose, a physics inspired weight map that takes the user input into account is proposed, which is used both as a feature map and in the system's loss function. Our approach is extensively evaluated on the public LIDC-IDRI dataset, where we achieve a state-of-the-art performance of 0.55 intersection over union vs the 0.59 inter-observer agreement. Also, we show that iW-Net allows to correct the segmentation of small nodules, essential for proper patient referral decision, as well as improve the segmentation of the challenging non-solid nodules and thus may be an important tool for increasing the early diagnosis of lung cancer.

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