Related references
Note: Only part of the references are listed.Biological Evaluation and Docking Analysis of Potent BACE1 Inhibitors from Boesenbergia rotunda
Kumju Youn et al.
NUTRIENTS (2019)
Acetylcholinesterase and Aβ Aggregation Inhibition by Heterometallic Ruthenium(II)-Platinum(II) Polypyridyl Complexes
Nilima A. Vyas et al.
INORGANIC CHEMISTRY (2018)
In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones
Seungeun Lee et al.
MOLECULES (2018)
Structure-activity relationship of eight high content flavonoids analyzed with a preliminary assign-score method and their contribution to antioxidant ability of flavonoids-rich extract from Scutellaria baicalensis shoots
Ke Li et al.
ARABIAN JOURNAL OF CHEMISTRY (2018)
Baicalein as a potent neuroprotective agent: A review
Kandhasamy Sowndhararajan et al.
BIOMEDICINE & PHARMACOTHERAPY (2017)
Therapeutic Potential of Baicalein in Alzheimer's Disease and Parkinson's Disease
Yanwei Li et al.
CNS DRUGS (2017)
The flavonoid baicalein rescues synaptic plasticity and memory deficits in a mouse model of Alzheimer's disease
Xun-Hu Gu et al.
BEHAVIOURAL BRAIN RESEARCH (2016)
Multiple-Ascending-Dose Pharmacokinetics and Safety Evaluation of Baicalein Chewable Tablets in Healthy Chinese Volunteers
Hongxian Pang et al.
CLINICAL DRUG INVESTIGATION (2016)
The amyloid hypothesis of Alzheimer's disease at 25years
Dennis J. Selkoe et al.
EMBO MOLECULAR MEDICINE (2016)
Baicalein improves behavioral dysfunction induced by Alzheimer's disease in rats
Li Zhou et al.
NEUROPSYCHIATRIC DISEASE AND TREATMENT (2016)
Deep Sequencing of the Scutellaria baicalensis Georgi Transcriptome Reveals Flavonoid Biosynthetic Profiling and Organ-Specific Gene Expression
Jinxin Liu et al.
PLOS ONE (2015)
Status of Acetylcholinesterase and Butyrylcholinesterase in Alzheimer's Disease and Type 2 Diabetes Mellitus
Gohar Mushtaq et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2014)
Effects of C-glycosylation on anti-diabetic, anti-Alzheimer's disease and anti-inflammatory potential of apigenin
Jae Sue Choi et al.
FOOD AND CHEMICAL TOXICOLOGY (2014)
Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects
Robert Vassar et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Development of a SPE-LC/MS/MS method for simultaneous quantification of baicalein, wogonin, oroxylin A and their glucuronides baicalin, wogonoside and oroxyloside in rats and its application to brain uptake and plasma pharmacokinetic studies
Sophia Yui Kau Fong et al.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2014)
Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model
She-Qing Zhang et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2013)
Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway
Francois Mouton-Liger et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
Pharmacokinetic study of baicalein after oral administration in monkeys
Shuo Tian et al.
FITOTERAPIA (2012)
Inhibition and structural reliability of prenylated flavones from the stem bark of Morus lhou on β-secretase (BACE-1)
Jung Keun Cho et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones
Chenrui Li et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2011)
The P-glycoprotein multidrug transporter
Frances J. Sharom
ESSAYS IN BIOCHEMISTRY: ABC TRANSPORTERS (2011)
β-Secretase inhibitor GRL-8234 rescues age-related cognitive decline in APP transgenic mice
Wan-Pin Chang et al.
FASEB JOURNAL (2011)
The Rule of Five for Non-Oral Routes of Drug Delivery: Ophthalmic, Inhalation and Transdermal
Young Bin Choy et al.
PHARMACEUTICAL RESEARCH (2011)
Neuroprotective Effect of Baicalein on Hydrogen Peroxide-Mediated Oxidative Stress and Mitochondrial Dysfunction in PC12 Cells
Shehua Zhang et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2010)
Post-injury baicalein improves histological and functional outcomes and reduces inflammatory cytokines after experimental traumatic brain injury
S-F Chen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Amyloid-cholinesterase interactions - Implications for Alzheimer's disease
Nibaldo C. Inestrosa et al.
FEBS JOURNAL (2008)
Crystal structure of an active form of BACE1, an enzyme responsible for amyloid beta protein production
Hideaki Shimizu et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases β-cleavage of amyloid precursor protein and amyloid-β production in vivo
Ishrut Hussain et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Potent inhibitory effect of flavonoids in Scutellaria baicalensis on amyloid β protein-induced neurotoxicity
HJ Heo et al.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)
Urinary pharmacokinetics of baicalein, wogonin and their glycosides after oral administration of scutellariae radix in humans
MY Lai et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2003)
The effects of the cyclosporin A, a P-glycoprotein inhibitor, on the pharmacokinetics of baicalein in the rat: a microdialysis study
TH Tsai et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
γ-Secretase, notch, Aβ and Alzheimer's disease:: Where do the presenilins fit in?
SS Sisodia et al.
NATURE REVIEWS NEUROSCIENCE (2002)
Baicalein protects cortical neurons from β-amyloid (25-35) induced toxicity
A Lebeau et al.
NEUROREPORT (2001)
Thioflavin T is a fluorescent probe of the acetylcholinesterase peripheral site that reveals conformational interactions between the peripheral and acylation sites
GV De Ferrari et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
BACE knockout mice are healthy despite lacking the primary β-secretase activity in brain:: implications for Alzheimer's disease therapeutics
SL Roberds et al.
HUMAN MOLECULAR GENETICS (2001)
Balicalin, the predominant flavone glucuronide of scutellariae radix, is absorbed from the rat gastrointestinal tract as the aglycone and restored to its original form
T Akao et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2000)