Related references
Note: Only part of the references are listed.Leptin is a physiological regulator of skeletal muscle angiogenesis and is locally produced by PDGFR and PDGFR expressing perivascular cells
Emmanuel Nwadozi et al.
ANGIOGENESIS (2019)
Physical activity and muscle-brain crosstalk
Bente Klarlund Pedersen
NATURE REVIEWS ENDOCRINOLOGY (2019)
iNOS Gene Ablation Prevents Liver Fibrosis in Leptin-Deficient ob/ob Mice
Sara Becerril et al.
GENES (2019)
The Impact of Childhood Obesity on Skeletal Health and Development
Paul Dimitri
JOURNAL OF OBESITY & METABOLIC SYNDROME (2019)
Foxc2 coordinates inflammation and browning of white adipose by leptin-STAT3-PRDM16 signal in mice
L. Gan et al.
INTERNATIONAL JOURNAL OF OBESITY (2018)
Targeted disruption of the iNOS gene improves adipose tissue inflammation and fibrosis in leptin-deficient ob/ob mice: role of tenascin C
S. Becerril et al.
INTERNATIONAL JOURNAL OF OBESITY (2018)
Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment
Kristin L. Ayers et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2018)
MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency
Karine Clement et al.
NATURE MEDICINE (2018)
The LepR-mediated leptin transport across brain barriers controls food reward
Alessandro Di Spiezio et al.
MOLECULAR METABOLISM (2018)
Crosstalk between adipokines and myokines in fat browning
A. Rodriguez et al.
ACTA PHYSIOLOGICA (2017)
Blood Pressure in Healthy Humans Is Regulated by Neuronal NO Synthase
Husain Shabeeh et al.
HYPERTENSION (2017)
Leptin stimulates bone formation in ob/ob mice at doses having minimal impact on energy metabolism
Kenneth A. Philbrick et al.
JOURNAL OF ENDOCRINOLOGY (2017)
The cellular and molecular bases of leptin and ghrelin resistance in obesity
Huxing Cui et al.
NATURE REVIEWS ENDOCRINOLOGY (2017)
The glucoregulatory actions of leptin
Anna M. D'souza et al.
MOLECULAR METABOLISM (2017)
Physical exercise remodels visceral adipose tissue and mitochondrial lipid metabolism in rats fed a high-fat diet
Silvia Rocha-Rodrigues et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2017)
Leptin dose-dependently decreases atherosclerosis by attenuation of hypercholesterolemia and induction of adiponectin
Annett Hoffmann et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2016)
Sex-dependent regulation of hypothalamic neuropeptide Y-Y1 receptor gene expression in leptin treated obese (ob/ob) or lean mice
Paolo Mele et al.
BRAIN RESEARCH (2016)
Adipose Tissue Hypoxia, Inflammation, and Fibrosis in Obese Insulin-Sensitive and Obese Insulin-Resistant Subjects
Helen M. Lawler et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism
Amaia Rodriguez et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2015)
Nitrate enhances skeletal muscle fatty acid oxidation via a nitric oxide-cGMP-PPAR-mediated mechanism
Tom Ashmore et al.
BMC BIOLOGY (2015)
Leptin and Insulin Act on POMC Neurons to Promote the Browning of White Fat
Garron T. Dodd et al.
CELL (2015)
Interactions between cocoa flavanols and inorganic nitrate: Additive effects on endothelial function at achievable dietary amounts
Ana Rodriguez-Mateos et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Significance of nitric oxide synthases: Lessons from triple nitric oxide synthases null mice
Masato Tsutsui et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2015)
Dietary nitrite supplementation improves insulin resistance in type 2 diabetic KKAy mice
Kazuo Ohtake et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2015)
Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice
Amaia Rodriguez et al.
SCIENTIFIC REPORTS (2015)
Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice
A. Rodriguez et al.
INTERNATIONAL JOURNAL OF OBESITY (2015)
Leptin Promotes Wound Healing in the Skin
Susumu Tadokoro et al.
PLOS ONE (2015)
Direct and indirect effects of leptin on adipocyte metabolism
Ruth B. S. Harris
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2014)
FNDC5 could be regulated by leptin in adipose tissue
Carolina Gutierrez-Repiso et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2014)
Leptin-cytokine crosstalk in breast cancer
Gale Newman et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2014)
Leptin Stimulates Both Endothelin-1 and Nitric Oxide Activity in Lean Subjects But Not in Patients With Obesity-Related Metabolic Syndrome
Francesca Schinzari et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)
Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis
Saurabh Chatterjee et al.
JOURNAL OF HEPATOLOGY (2013)
Evidence for two types of brown adipose tissue in humans
Martin E. Lidell et al.
NATURE MEDICINE (2013)
Leptin Potentiates Endothelium-Dependent Relaxation by Inducing Endothelial Expression of Neuronal NO Synthase
Sebastian Benkhoff et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2012)
Increased Tenascin C And Toll-Like Receptor 4 Levels in Visceral Adipose Tissue as a Link between Inflammation and Extracellular Matrix Remodeling in Obesity
Victoria Catalan et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
Pontus Bostroem et al.
NATURE (2012)
Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance
Rebecca L. Leshan et al.
NATURE MEDICINE (2012)
Transcriptional analysis of brown adipose tissue in leptin-deficient mice lacking inducible nitric oxide synthase: evidence of the role of Med1 in \energy balance
Sara Becerril et al.
PHYSIOLOGICAL GENOMICS (2012)
Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice
Neira Sainz et al.
PLOS ONE (2012)
Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans
Filip J. Larsen et al.
CELL METABOLISM (2011)
Vascular Endothelial Growth Factor Receptor-2 Couples Cyclo-Oxygenase-2 with Pro-Angiogenic Actions of Leptin on Human Endothelial Cells
Elena Garonna et al.
PLOS ONE (2011)
Leptin Induces Phosphorylation of Neuronal Nitric Oxide Synthase in Defined Hypothalamic Neurons
Jose Donato et al.
ENDOCRINOLOGY (2010)
Involvement of serum vascular endothelial growth factor family members in the development of obesity in mice and humans
Javier Gomez-Ambrosi et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2010)
Leptin Inhibits the Proliferation of Vascular Smooth Muscle Cells Induced by Angiotensin II through Nitric Oxide-Dependent Mechanisms
Amaia Rodriguez et al.
MEDIATORS OF INFLAMMATION (2010)
Deletion of Inducible Nitric-Oxide Synthase in Leptin-Deficient Mice Improves Brown Adipose Tissue Function
Sara Becerril et al.
PLOS ONE (2010)
Angiogenesis, adipokines and breast cancer
Linda Vona-Davis et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2009)
Inhibitory Effects of Leptin on Pancreatic α-Cell Function
Eva Tuduri et al.
DIABETES (2009)
Leptin Indirectly Regulates Gonadotropin-Releasing Hormone Neuronal Function
Janette H. Quennell et al.
ENDOCRINOLOGY (2009)
Role of arginine in superficial wound healing in man
I. B. J. G. Debats et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2009)
Leptin Administration Favors Muscle Mass Accretion by Decreasing FoxO3a and Increasing PGC-1α in ob/ob Mice
Neira Sainz et al.
PLOS ONE (2009)
PRDM16: the interconvertible adipo-myocyte switch
Gema Fruhbeck et al.
TRENDS IN CELL BIOLOGY (2009)
Insulin and leptin enhance human sperm motility, acrosome reaction and nitric oxide production
Fanuel Lampiao et al.
ASIAN JOURNAL OF ANDROLOGY (2008)
Ghrelin induces growth hormone secretion via a nitric oxide/cGMP signalling pathway
F. Rodriguez-Pacheco et al.
JOURNAL OF NEUROENDOCRINOLOGY (2008)
Neuronal nitric oxide synthase contributes to the regulation of hematopoiesis
Peter Krasnov et al.
MOLECULAR MEDICINE (2008)
Expression of caveolin-1 in human adipose tissue is upregulated in obesity and obesity-associated type 2 diabetes mellitus and related to inflammation
Victoria Catalan et al.
CLINICAL ENDOCRINOLOGY (2008)
Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma synergistic NOS type II induction in chondrocytes
Miguel Otero et al.
LIFE SCIENCES (2007)
Adipose tissue expression of the glycerol channel aquaporin-7 gene is altered in severe obesity but not in type 2 diabetes
V. Ceperuelo-Mallafre et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
Nitric oxide synthase inhibition prevents leptin induced Gn-RH release in prepubertal and peripubertal female rats
R. Reynoso et al.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2007)
Role of caveolins in body weight and insulin resistance regulation
Gema Fruhbeck et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2007)
Angiogenesis modulates adipogenesis and obesity
Yihai Cao
JOURNAL OF CLINICAL INVESTIGATION (2007)
The inhibitory effect of leptin on angiotensin II-induced vasoconstriction in vascular smooth muscle cells is mediated via a nitric oxide-dependent mechanism
Amaia Rodriguez et al.
ENDOCRINOLOGY (2007)
Effects of dietary nitrate on blood pressure in healthy volunteers
Filip J. Larsen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Involvement of leptin signaling in the survival and maturation of bone marrow-derived dendritic cells
Queenie Lai Kwan Lam et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Convergence between bone and energy homeostases: Leptin regulation of bone mass
Gerard Karsenty
CELL METABOLISM (2006)
The severely obese patient - a genetic work-up
S Farooqi
NATURE CLINICAL PRACTICE ENDOCRINOLOGY & METABOLISM (2006)
Leptin modulates nitric oxide production and lipid metabolism in human placenta
V White et al.
REPRODUCTION FERTILITY AND DEVELOPMENT (2006)
Oxidative stress and nitric oxide deficiency in the kidney: a critical link to hypertension?
CS Wilcox
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)
Neuronal nitric oxide synthase controls enzyme activity pattern of mitochondria and lipid metabolism
L Schild et al.
FASEB JOURNAL (2005)
Caveolin; different roles for insulin signal?
Y Ishikawa et al.
CELLULAR SIGNALLING (2005)
Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1
LA Ridnour et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms
T Morishita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Leptin receptors are expressed in coronary arteries, and hyperleptinemia causes significant coronary endothelial dysfunction
JD Knudson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2005)
Interaction between nitric oxide and the cholinergic and sympathetic nervous system in cardiovascular control in humans
C Sartori et al.
PHARMACOLOGY & THERAPEUTICS (2005)
A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice
M Fujimoto et al.
DIABETES (2005)
Acute central infusion of leptin modulates fatty acid mobilization by affecting lipolysis and mRNA expression for uncoupling proteins
D Tajima et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2005)
The hypothalamic arcuate nucleus: A key site for mediating leptin's effects on glucose homeostasis and locomotor activity
R Coppari et al.
CELL METABOLISM (2005)
Inducible nitric oxide synthase modulates lipolysis in adipocytes
P Penfornis et al.
JOURNAL OF LIPID RESEARCH (2005)
The weight of leptin in immunity
A La Cava et al.
NATURE REVIEWS IMMUNOLOGY (2004)
Nitric oxide/nitric oxide synthase, spermatogenesis, and tight junction dynamics
NPY Lee et al.
BIOLOGY OF REPRODUCTION (2004)
Inhibited anabolic effect of insulin-like growth factor-I on stromal bone marrow cells in endothelial nitric oxide synthase-knockout mice
A Lagumdzija et al.
ACTA PHYSIOLOGICA SCANDINAVICA (2004)
Nitric oxide is a regulator of hematopoietic stem cell activity
T Michurina et al.
MOLECULAR THERAPY (2004)
Reduced adipose tissue mass and hypoleptinemia in NOS deficient mice:: effect of LPS on plasma leptin and adiponectin concentrations
J Gómez-Ambrosi et al.
FEBS LETTERS (2004)
Effects of chronic nitric oxide inhibition on the renal excretory response to leptin
D Villarreal et al.
OBESITY RESEARCH (2004)
Leptin induces growth hormone secretion from peripheral blood mononuclear cells via a protein kinase C- and nitric oxide-dependent mechanism
VD Dixit et al.
ENDOCRINOLOGY (2003)
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
A Aicher et al.
NATURE MEDICINE (2003)
Leptin expression in the rat ovary depends on estrous cycle
M Archanco et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2003)
Leptin is an autocrine/paracrine regulator of wound healing
A Murad et al.
FASEB JOURNAL (2003)
Leptin in the CNS: much more than a satiety signal
J Harvey et al.
NEUROPHARMACOLOGY (2003)
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
E Nisoli et al.
SCIENCE (2003)
Control of body weight:: a physiologic and transgenic perspective
G Frühbeck et al.
DIABETOLOGIA (2003)
Obesity is associated with macrophage accumulation in adipose tissue
SP Weisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2003)
The role of nitric oxide (NO) in control of LHRH release that mediates gonadotropin release and sexual behavior
SM McCann et al.
CURRENT PHARMACEUTICAL DESIGN (2003)
Site-specific dephosphorylation of endothelial nitric oxide synthase by protein phosphatase 2A: Evidence for crosstalk between phosphorylation sites
DM Greif et al.
BIOCHEMISTRY (2002)
Nitric oxide preferentially induces type 1 T cell differentiation by selectively up-regulating IL-12 receptor β2 expression via cGMP
W Niedbala et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation
ZG Tian et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Leptin regulates bone formation via the sympathetic nervous system
S Takeda et al.
CELL (2002)
Leptin potentiates IFN-γ-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1
GM Raso et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo
J Cornish et al.
JOURNAL OF ENDOCRINOLOGY (2002)
Influence of leptin on arterial distensibility - A novel link between obesity and cardiovascular disease?
A Singhal et al.
CIRCULATION (2002)
Leptin improves membrane fluidity of erythrocytes in humans via a nitric oxide-dependent mechanism - an electron paramagnetic resonance investigation
K Tsuda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Immunocytochemical detection of leptin in non-mammalian vertebrate stomach
FJ Muruzábal et al.
GENERAL AND COMPARATIVE ENDOCRINOLOGY (2002)
The ingestion of inorganic nitrate increases gastric S-nitrosothiol levels and inhibits platelet function in humans
G Richardson et al.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY (2002)
Resting and circadian release of nitric oxide is controlled by leptin in male rats
CA Mastronardi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Leptin-deficient mice exhibit impaired host defense in gram-negative pneumonia
P Mancuso et al.
JOURNAL OF IMMUNOLOGY (2002)
Energy metabolism and expression of uncoupling proteins 1, 2, and 3 after 21 days of recovery from intracerebroventricular mouse leptin in rats
PS Gullicksen et al.
PHYSIOLOGY & BEHAVIOR (2002)
Evidence for a functional nitric oxide synthase system in brown adipocyte nucleus
A Giordano et al.
FEBS LETTERS (2002)
Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling
JO Gordeladze et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2002)
Leptin effect on endothelial nitric oxide is mediated through Akt-endothelial nitric oxide synthase phosphorylation pathway
C Vecchione et al.
DIABETES (2002)
Modulation of the leptin-induced white adipose tissue lipolysis by nitric oxide
G Frühbeck et al.
CELLULAR SIGNALLING (2001)
Severe hypercholesterolemia, hypertriglyceridemia, and atherosclerosis in mice lacking both leptin and the low density lipoprotein receptor
AH Hasty et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle
M Perreault et al.
NATURE MEDICINE (2001)
Nitric oxide in parasitic infections
LR Brunet
INTERNATIONAL IMMUNOPHARMACOLOGY (2001)
Nitric oxide in immunity and inflammation
JW Coleman
INTERNATIONAL IMMUNOPHARMACOLOGY (2001)
Potential role of leptin in angiogenesis:: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro
HY Park et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2001)
Obesity hypertension: Role of leptin and sympathetic nervous system
JE Hall et al.
AMERICAN JOURNAL OF HYPERTENSION (2001)
Leptin induces vascular permeability and synergistically stimulates angiogenesis with FGF-2 and VEGF
RH Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Rapid in vivo PGC-1 mRNA upregulation in brown adipose tissue of Wistar rats by a β3-adrenergic agonist and lack of effect of leptin
J Gómez-Ambrosi et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2001)
Leptin in reproduction
M Caprio et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2001)
Role of leptin in ulcer healing
PC Konturek et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Leptin-induced lipolysis opposes the tonic inhibition of endogenous adenosine in white adipocytes
G Frühbeck et al.
FASEB JOURNAL (2001)
Lipotoxic diseases of nonadipose tissues in obesity
RH Unger et al.
INTERNATIONAL JOURNAL OF OBESITY (2000)
Leptin attenuates cardiac contraction in rat ventricular myocytes - Role of NO
MW Nickola et al.
HYPERTENSION (2000)
Nitric oxide-dependent downregulation of adipocyte UCP-2 expression by tumor necrosis factor-α
C Merial et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2000)
Requirement of the inducible nitric oxide synthase pathway for IL-1-induced osteoclastic bone resorption
RJ van't Hof et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Leptin inhibits bone formation through a hypothalamic relay: A central control of bone mass
P Ducy et al.
CELL (2000)
Effects of renal denervation on the sodium excretory actions of leptin in hypertensive rats
D Villarreal et al.
KIDNEY INTERNATIONAL (2000)
Relation between leptin and the regulation of glucose metabolism
G Fruhbeck et al.
DIABETOLOGIA (2000)