Journal
MATERIALS
Volume 12, Issue 18, Pages -Publisher
MDPI
DOI: 10.3390/ma12182991
Keywords
scaffold; graphene oxide; polycaprolactone; supercritical foaming; flexible composite
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Funding
- Russian Foundation for Basic Research [18-29-06071]
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Developing bone scaffolds can greatly improve the patient's quality of life by accelerating the rehabilitation process. In this paper, we studied the process of composite polycaprolactone supercritical foaming for tissue engineering. The influence of graphene oxide and reduced graphene oxide on the foaming parameters was studied. The structural and mechanical properties were studied. The scaffolds demonstrated mechanical flexibility and endurance. The co-culturing and live/dead tests demonstrated that the obtained scaffolds are biocompatible. Different composite scaffolds induced various surface cell behaviors. The experimental data demonstrate that composite foams are promising candidates for in vivo medical trials.
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