Journal
BIOPHYSICAL JOURNAL
Volume 109, Issue 6, Pages 1082-1086Publisher
CELL PRESS
DOI: 10.1016/j.bpj.2015.04.020
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Funding
- European Molecular Biology Laboratory (EMBL)
- MRC [MR/K020420/1] Funding Source: UKRI
- Medical Research Council [MR/K020420/1] Funding Source: researchfish
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Enzymes are the proteins responsible for the catalysis of life. Enzymes sharing a common ancestor as defined by sequence and structure similarity are grouped into families and superfamilies. The molecular function of enzymes is defined as their ability to catalyze biochemical reactions; it is manually classified by the Enzyme Commission and robust approaches to quantitatively compare catalytic reactions are just beginning to appear. Here, we present an overview of studies at the interface of the evolution and function of enzymes.
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