Journal
JOURNAL OF FUNCTIONAL FOODS
Volume 64, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jff.2019.103643
Keywords
Bacillus coagulans; Digestion; Metabolism; Microbiota; Immune system; Human diseases
Categories
Funding
- National Natural Science Foundation of China Program [31820103010, 31530056]
- Natural Science Foundation of Jiangsu Province of China [BK20141098, BK20160175]
- National First-Class Discipline Program of Food Science and Technology [JUFSTR20180102]
- BBSRC Newton Fund Joint Centre Award
- Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province
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As a spore-forming probiotic bacterium, Bacillus coagulans has become a focus of research due to its high tolerance of extreme environments and probiotic characteristics. Several beneficial effects of B. coagulans have been reported. Firstly, B. coagulans can promote intestinal digestion. For example, B. coagulans strains can produce various enzymes that facilitate excretion and digestion. Secondly, B. coagulans can regulate host symbiotic microbiota and inhibit the growth of pathogenic bacteria. Lastly, due to its ability to normalize both the quantitative parameters of the immune system and immune cells' functional activity, B. coagulans can significantly benefit the host immune system. Due to the evidence supporting various probiotic effects of B. coagulans, many B. coagulans strains have been studied in the management and alleviation of several human diseases. Therefore, the administration of B. coagulans may be an attractive preventive and/or therapeutic approach for human diseases.
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