Journal
BIOTECHNOLOGY ADVANCES
Volume 34, Issue 8, Pages 1396-1412Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.biotechadv.2016.10.005
Keywords
Microalgae; Carotenoids; Extraction; Astaxanthin; Lutein; beta-Carotene; Harvesting; Downstream processing; Cell disruption
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Funding
- NSERC Discovery Grant [170124-2011 RGPIN]
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Carotenoids have been receiving increasing attention due to their potential health benefits. Microalgae are recognized as a natural source of carotenoids and other beneficial byproducts. However, the production of micro-algal carotenoids is not yet sufficiently cost-effective to compete with traditional chemical synthetic methods and other technologies such as extraction from plant based sources. This review presents the recent biotechnological developments in microalgal carotenoid production. The current technologies involved in their bioprocessing including cultivation, harvesting, extraction, and purification are discussed with a specific focus on downstream processing. The recent advances in chemical and biochemical synthesis of carotenoids are also reviewed for a better understanding of suitable and economically feasible biotechnological strategies. Some possible future directions are also proposed. (C) 2016 Elsevier Inc All rights reserved.
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